Subject(s)
Foreign Bodies/diagnosis , Ileal Diseases/etiology , Intestinal Perforation/etiology , Meckel Diverticulum/complications , Seafood/adverse effects , Adolescent , Bone and Bones , Foreign Bodies/complications , Humans , Ileal Diseases/diagnosis , Intestinal Perforation/diagnosis , Male , Meckel Diverticulum/diagnosisABSTRACT
A 45-year-old female presented at our hospital with a one-day history of upper abdominal pain. Abdominal computed tomography (CT) revealed that the root of the celiac artery was obstructed and that a large hematoma was present in the retroperitoneum. The patient was diagnosed with retroperitoneal hemorrhage associated with the rupture of an inferior pancreaticoduodenal artery aneurysm, which was caused by increased blood flow in the pancreaticoduodenal arterial arcade. Because the patient's general condition was stable, she was managed conservatively and discharged on achieving remission after a month. Follow-up CT revealed spontaneous resolution of the celiac artery obstruction and aneurysm. The celiac artery obstruction in this case was assumed to be caused by segmental arterial mediolysis.
Subject(s)
Aneurysm, Ruptured/therapy , Arterial Occlusive Diseases/complications , Celiac Artery , Duodenum/blood supply , Pancreas/blood supply , Aneurysm, Ruptured/etiology , Female , Humans , Middle AgedABSTRACT
BACKGROUND: Argyrophilic nucleolar organizer regions (AgNORs) and MIB-1 as proliferating activities have been applied separately to assess the malignant potential of cancer cells. We conducted staining of AgNORs and MIB-1 in 42 surgically-resected invasive breast carcinomas. MATERIALS AND METHODS: Paraffin-embedded sections were used for double staining and the mean AgNOR counts in 100 MIB-1-positive and -negative cells were calculated. RESULTS: The mean AgNOR count in MIB-1-positive cells was significantly higher than in MIB-1-negative ones. AgNOR counts in MIB-1-positive tumors were significantly higher in tumors > or =2 cm and those with positive nodes. Multivariate analysis identified the AgNOR count in MIB-1-positive tumors as the only independent factor related to node metastasis. Survival of patients with lower counts of AgNORs in MIB-1-positive tumors was significantly better compared to those with higher counts. CONCLUSION: Double staining of MIB-1 and AgNORs is useful for predicting lymph node metastasis and prognosis of patients with breast carcinoma.
Subject(s)
Antigens, Nuclear/analysis , Breast Neoplasms/metabolism , Breast Neoplasms/pathology , Ki-67 Antigen/analysis , Nuclear Proteins/analysis , Adult , Aged , Aged, 80 and over , Breast Neoplasms/surgery , Cell Growth Processes , Female , Humans , Immunohistochemistry , Middle Aged , Multivariate Analysis , Prognosis , Staining and Labeling/methodsABSTRACT
Islet cell tumors of the pancreas are uncommon, and nonfunctioning tumors are even rarer than functioning ones. We report the case of a 67-year-old woman with a small nonfunctioning islet cell tumor, 6 x 5 mm in diameter, which was detected incidentally by ultrasonography, and subsequently confirmed by double-helical computed tomography. Diagnosis was established by histopathological examination after 80% distal pancreatectomy with splenectomy, and by various laboratory tests. Histologically, the islet cell tumor showed highly cellular spindle or epithelioid cells, which were positive for Grimelius stain. Immunohistochemical examination revealed that the tumor cells were positive for chromogranin A, but negative for somatostatin, insulin, glucagon, and gastrin. Its small size, location, and benignity make this a very rare type of nonfunctioning islet cell tumor.
