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Rofo ; 176(2): 252-7, 2004 Feb.
Article in German | MEDLINE | ID: mdl-14872381

ABSTRACT

PURPOSE: Exact preoperative determination of the liver volume is of great importance prior to hepatobiliary surgery, especially in living donated liver transplantation (LDLT). In the current literature, a strong correlation between preoperatively calculated and intraoperatively measured liver volumes has been described. Such accuracy seems questionable, primarily due to a difference in the perfusion state of the liver in situ versus after explantation. Purpose of the study was to asses the influence of the perfusion state on liver volume and the validity of the preoperative liver volumetry prior to LDLT. METHODS: In an experimental study, 20 porcine livers were examined. The livers were weighted and their volumes were determined by water displacement prior and after fluid infusion to achieve a pressure physiologically found in the liver veins. The liver volumes in the different perfusion states were calculated based on CT-data. The calculated values were compared with the volume measured by water displacement and the weight of the livers. RESULTS: Assessment of calculated CT volumes and water displacements at identical perfusion states showed a tight correlation and differed on average by 4 +/- 5 %. However, livers before and after fluid infusion showed a 33 +/- 8 % (350 +/- 150 ml) difference in volume. CONCLUSION: CT-volumetry acquires highly accurate data as confirmed by water displacement studies. However, the perfusion state has major impact on liver volume, which has to be accounted for in clinical use.


Subject(s)
Liver Transplantation , Liver/anatomy & histology , Liver/diagnostic imaging , Living Donors , Tomography, X-Ray Computed/methods , Animals , Organ Size , Swine
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