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Jpn J Infect Dis ; 74(3): 240-244, 2021 May 24.
Article in English | MEDLINE | ID: mdl-33132300

ABSTRACT

The prevalence of quinolone- and macrolide-resistant Group B Streptococcus (GBS) is increasing worldwide, but the relationship between the resistance of GBS to these antibiotics and patient outcome remains unclear. Therefore, we evaluated whether blood stream infection caused by quinolone- or macrolide-resistant GBS is associated with high mortality. Our findings in 77 patients with GBS bacteremia demonstrate that quinolone and macrolide resistance may not be risk factors for 30-day mortality.


Subject(s)
Bacteremia , Macrolides/pharmacology , Quinolines/pharmacology , Streptococcal Infections/drug therapy , Streptococcal Infections/epidemiology , Streptococcus agalactiae/drug effects , Adolescent , Adult , Aged , Aged, 80 and over , Bacteremia/drug therapy , Bacteremia/epidemiology , Bacteremia/microbiology , Cause of Death , Child , Cohort Studies , Drug Resistance, Multiple, Bacterial/drug effects , Female , Humans , Japan/epidemiology , Male , Microbial Sensitivity Tests , Middle Aged , Mortality , Treatment Outcome , Young Adult
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