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Nihon Kokyuki Gakkai Zasshi ; 42(2): 181-4, 2004 Feb.
Article in Japanese | MEDLINE | ID: mdl-15007920

ABSTRACT

Small cell lung cancer was diagnosed in a 54-year-old man in 1997. He had received 5 cycles of systemic chemotherapy and thoracic irradiation since 1997, and a favorable response had been achieved. In August 2001, pro-GRP was again elevated, and he was readmitted. Bronchoscopic findings revealed a white dendritic endobronchial mass on a cheese-like plug obstructing the left upper bronchus division. Numerous mucor hyphe and cancer cells were detected by transbronchial biopsy, and a fungal culture disclosed mucor. Although no antifungal drug was administered, the bronchial lesion disappeared after removal with biopsy forceps and 2 cycles of systemic anticancer chemotherapy. Endobronchial involvement of mucormycosis is rare and this case is unique because of the peculiar bronchoscopic finding with the endobronchial lesion.


Subject(s)
Bronchial Diseases/etiology , Bronchial Diseases/pathology , Bronchoscopy , Carcinoma, Small Cell/complications , Lung Neoplasms/complications , Mucormycosis/etiology , Mucormycosis/pathology , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Biopsy/methods , Bronchial Diseases/therapy , Carcinoma, Small Cell/therapy , Cisplatin/administration & dosage , Humans , Immunocompromised Host , Lung Neoplasms/therapy , Male , Middle Aged , Mucormycosis/therapy , Paclitaxel/administration & dosage , Rhizomucor , Surgical Instruments , Treatment Outcome
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