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1.
Semin Neurol ; 43(3): 388-396, 2023 06.
Article in English | MEDLINE | ID: mdl-37562448

ABSTRACT

Dural arteriovenous fistulas (DAVFs) are abnormal communications between meningeal arteries and dural venous sinuses and/or cortical veins. Although many fistulas are benign and do not require treatment, some may carry a significant risk of bleeding or cause symptoms and warrant treatment. This review provides a review of various aspects of intracranial DAVFs including epidemiology, pathophysiology, clinical presentation, imaging characteristics, classification, natural history, and management options. By exploring these topics, we aim to enhance understanding of this condition and facilitate patient care.


Subject(s)
Central Nervous System Vascular Malformations , Embolization, Therapeutic , Humans , Cranial Sinuses , Central Nervous System Vascular Malformations/diagnostic imaging , Central Nervous System Vascular Malformations/epidemiology , Cerebral Angiography
2.
Semin Neurol ; 43(3): 408-418, 2023 06.
Article in English | MEDLINE | ID: mdl-37536373

ABSTRACT

Pediatric neurovascular disorders can lead to substantial mortality and morbidity if not diagnosed early and adequately managed. Children with neurovascular diseases cannot be treated as small adults as the vascular and central nervous system anatomy, physiology, and pathologies in children differ greatly from those of adults. In addition, some neurovascular pathologies are seen exclusively in children such as aneurysmal malformation of the vein of Galen, pial fistulas, and dural fistulas in the context of dural sinus disease. In this review, we aim to present an overview of the common pediatric neurovascular diseases along with their endovascular management.


Subject(s)
Central Nervous System Vascular Malformations , Intracranial Arteriovenous Malformations , Child , Adult , Humans , Central Nervous System Vascular Malformations/diagnostic imaging , Central Nervous System Vascular Malformations/therapy , Intracranial Arteriovenous Malformations/diagnostic imaging , Intracranial Arteriovenous Malformations/therapy , Cranial Sinuses , Central Nervous System
3.
Front Neurol ; 13: 1016376, 2022.
Article in English | MEDLINE | ID: mdl-36408502

ABSTRACT

Background: Acute stroke care is complex and requires multidisciplinary networking. There are insufficient data on stroke care in the Middle East and adjacent regions in Asia and Africa. Objective: Evaluate the state of readiness of stroke programs in the Middle East North Africa and surrounding regions (MENA+) to treat acute stroke. Method: Online questionnaire survey on the evaluation of stroke care across hospitals of MENA+ region between April 2021 and January 2022. Results: The survey was completed by 34/50 (68%) hospitals. The median population serviced by participating hospitals was 2 million. The median admission of patients with stroke/year was 600 (250-1,100). The median length of stay at the stroke units was 5 days. 34/34 (100%) of these hospitals have 24/7 CT head available. 17/34 (50%) have emergency guidelines for prehospital acute stroke care. Mechanical thrombectomy with/without IVT was available in 24/34 (70.6%). 51% was the median (IQR; 15-75%) of patients treated with IVT within 60 min from arrival. Thirty-five minutes were the median time to reverse warfarin-associated ICH. Conclusion: This is the first large study on the availability of resources for the management of acute stroke in the MENA+ region. We noted the disparity in stroke care between high-income and low-income countries. Concerted efforts are required to improve stroke care in low-income countries. Accreditation of stroke programs in the region will be helpful.

4.
J Clin Med ; 10(13)2021 Jul 01.
Article in English | MEDLINE | ID: mdl-34279454

ABSTRACT

Autoimmune brainstem encephalitis (BSE) is a rare neurological condition with a wide range of underlying etiologies. It can be subdivided into two broad groups: a primary inflammatory disease of the central nervous system (CNS) or a brainstem disorder secondary to systemic diseases where the CNS is only one of many affected organs. Symptoms range from mild to life-threatening manifestations. Most cases respond well to immunotherapy. Therefore, broad and in-depth knowledge of the various inflammatory disorders that target the brainstem is essential for guiding the diagnostic approach and assisting in early initiation of appropriate therapy. We herein report on a case of BSE and provide an overview of the various causes of autoimmune BSE with an emphasis on the clinical manifestations and diagnostic approach.

5.
Surg Radiol Anat ; 43(5): 749-753, 2021 May.
Article in English | MEDLINE | ID: mdl-33136184

ABSTRACT

PURPOSE: The palmaris longus (PL) tendon present a high degree of variations; the commonest is its absence which could reach more than 40% in some populations. The PL tendon is highly relevant in hand reconstructive surgery; however, MRI variations of PL tendon have been exceptionally reported. To this, this study investigated PL tendon variations using MRI in a Lebanese population. METHODS: This is a retrospective study of distal forearm MRI examinations to evaluate the presence, anatomical variations and morphometric of PL tendon. The outcomes were set as overall frequency, gender-based and side-base frequencies, correlations between prevalence and gender/side, morphological variants, thickness, and width of PL tendon. RESULTS: The sample comprised 335 patients including a total of 339 MRI scans. The PL was present in 221 wrists (65.2%), and bilaterally in only one (25%) out of the 4 bilateral cases. All PL were located using the Axial T1 views. Univariate and multivariate analyses showed no correlation with side, gender, or Tesla power. The only morphological variation was a reversed PL in 2 cases (0.6%). The mean width was 4.24 ± 1.2 mm. The mean thickness was 2.75 ± 0.6 mm. CONCLUSION: As far as we know, this is the first study to report the total array of variations of PL tendon using MRI, and its prevalence in a Lebanese population. The mean width of PL tendon calculated with high quality MR imaging was found to be similar to that reported by cadaveric studies.


Subject(s)
Anatomic Variation , Forearm/anatomy & histology , Hand/anatomy & histology , Tendons/anatomy & histology , Adult , Female , Forearm/diagnostic imaging , Hand/surgery , Humans , Lebanon/epidemiology , Magnetic Resonance Imaging , Male , Middle Aged , Prevalence , Plastic Surgery Procedures , Retrospective Studies , Tendons/diagnostic imaging , Young Adult
8.
World Neurosurg ; 134: 123-127, 2020 Feb.
Article in English | MEDLINE | ID: mdl-31689569

ABSTRACT

BACKGROUND: The incidence of Moyamoya disease (MMD)-associated intracranial aneurysms ranges from 3% to 14% in adult patients, whereas this complication has rarely been reported in children. CASE DESCRIPTION: We herein report the first case, to our knowledge, of an extremely rare subarachnoid hemorrhage presentation of a child with a ruptured anterior cerebral artery dissecting aneurysm secondary to a newly discovered, unilateral Moyamoya-like pathology. CONCLUSIONS: MMD-associated aneurysms are extremely rare in children, and hemorrhage may be the initial presentation of the disease. Prompt intervention is essential to exclude the ruptured aneurysm that is at risk of rebleeding because of persistent hemodynamic stress.


Subject(s)
Cerebral Arterial Diseases/etiology , Intracranial Aneurysm/etiology , Moyamoya Disease/complications , Subarachnoid Hemorrhage/etiology , Adolescent , Aneurysm, Ruptured/etiology , Female , Humans
9.
Brain Inj ; 31(10): 1396-1397, 2017.
Article in English | MEDLINE | ID: mdl-28627931

ABSTRACT

We herein report a unique case of a lateral pontine demyelinating lesion presenting with unilateral sensorineural hearing loss and paradoxical ipsilateral hyperacusis. The association of unilateral hearing loss and ipsilateral hyperacusis is a rare manifestation of a central nervous system lesion. The paradoxical combination of these symptoms strongly suggests pontine dysfunction and prompts urgent neurological evaluation.


Subject(s)
Demyelinating Diseases/diagnosis , Hearing Loss, Sensorineural/diagnosis , Hyperacusis/diagnosis , Pons/pathology , Adult , Demyelinating Diseases/diagnostic imaging , Demyelinating Diseases/pathology , Hearing Loss, Sensorineural/diagnostic imaging , Hearing Loss, Sensorineural/pathology , Humans , Hyperacusis/diagnostic imaging , Hyperacusis/pathology , Magnetic Resonance Imaging , Male , Pons/diagnostic imaging , Syndrome
11.
Semin Intervent Radiol ; 27(4): 327-37, 2010 Dec.
Article in English | MEDLINE | ID: mdl-22550374

ABSTRACT

Modern interventional radiology practice is continuously evolving. Developments include increases in the number of central venous catheter placements and tumor treatments (uterine fibroid therapy, radio- and chemoembolization of liver tumor, percutaneous radiofrequency and cryoablation), and new procedures such as abdominal aortic aneurysm stent-graft repair, vertebroplasty, kyphoplasty, and varicose vein therapies. There have also been recent advancements in standard biliary and urinary drainage procedures, percutaneous gastrointestinal feeding tube placement, and transjugular intrahepatic portosystemic shunts. Prophylactic antibiotics have become the standard of care in many departments, with little clinical data to support its wide acceptance. The rise in antibiotic-resistant strains of organisms in all hospitals worldwide have forced every department to question the use of prophylactic antibiotics. The authors review the evidence behind use of prophylactic antibiotics in standard interventional radiology procedures, as well as in newer procedures that have only recently been incorporated into interventional radiology practice.

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