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1.
Zentralbl Veterinarmed A ; 36(9): 676-86, 1989 Nov.
Article in German | MEDLINE | ID: mdl-2514527

ABSTRACT

A pig grower ration containing olaquindox at a concentration of 778 mg/kg was accidentally fed to 10 respectively 16 weeks old weaner pigs. The subsequent intoxication was characterized by poor growth and long-term disturbances of renal function and electrolyte metabolism. A deficiency of aldosterone, produced by a selective degeneration of the arcuate zone of the adrenal cortex, is probably the cause of the hyponatremia, hyperkalemia and hemoconcentration observed. Simultaneously plasma levels of urea and creatinine were elevated five- to eightfold. Due to hyperkalemia episodes with collapse, paralysis and severe electrocardiographic changes occurred several times. Two pigs died in the course of such attacks. Individuals, which transiently showed distinct clinical symptoms of intoxication, did not show any signs of disease 15 or 18 weeks later. Therefore it may be assumed, that the lesions of the adrenals, heart and skeletal muscle caused by olaquindox intoxication are reversible in some cases.


Subject(s)
Quinoxalines/poisoning , Swine Diseases/chemically induced , Animals , Blood Proteins/analysis , Hematocrit/veterinary , Hemoglobins/analysis , Swine , Swine Diseases/blood
2.
Dtsch Tierarztl Wochenschr ; 96(4): 216-22, 1989 Apr.
Article in German | MEDLINE | ID: mdl-2653783

ABSTRACT

The paper describes pathomorphological findings in two dogs and one cat with the intention to clarify whether these animals died by drowning. The investigations are supplemented by experimental results of water instillation into the lung to induce signs of emphysema aquosum post mortem. Additionally, histopathology of the skin lesions due to water exposition after death are demonstrated by systematic investigations of four different localizations for 10 days. Critical evaluation of the results and literature references in human forensic pathology indicate that post mortem findings as described in this paper, especially those of the so called "drowning lung" can be attributed to death by drowning.


Subject(s)
Cats , Dogs , Drowning/veterinary , Animals , Drowning/pathology , Female , Lung/pathology , Male , Skin/pathology
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