ABSTRACT
Hydroa vacciniforme is a rare acquired photosensitivity disorder that manifests in childhood. We sought to identify the demographics, disease progression, symptoms, risk factors, and treatment efficacy associated with hydroa vacciniforme using a questionnaire. Nineteen surveys were included in the data analysis. Symptoms occurred throughout the year and the most common dermatologic manifestations included redness, blisters, bumps, scars, itching, and burning, predominantly on sun-exposed areas. The most common associated symptoms included oral ulcers, abdominal pain, and eye ulcers. Most participants limited their sun exposure to less than 10 hours weekly and stated sunscreen somewhat helped prevent breakouts. Most participants had no to limited improvement of their symptoms with treatments.
Subject(s)
Hydroa Vacciniforme/pathology , Adolescent , Adult , Age of Onset , Child , Child, Preschool , Disease Progression , Female , Humans , Hydroa Vacciniforme/diagnosis , Hydroa Vacciniforme/epidemiology , Hydroa Vacciniforme/prevention & control , Male , New York/epidemiology , Phototherapy/methods , Quality of Life , Risk Factors , Sunscreening Agents/therapeutic use , Surveys and Questionnaires , Treatment OutcomeABSTRACT
Methicillin-resistant Staphylococcus aureus (MRSA) is increasingly becoming a major source of systemic infection in the community and healthcare settings. The disease is responsible for deaths among individuals without known risk factors and presents a therapeutic challenge for clinicians because of the bacteria's complex epidemiology and mechanisms of antibiotic resistance. Furthermore, the skin and soft tissue are the most commonly infected organs. Consequently it is necessary for the dermatologist to have an understanding of the management of the condition to prevent lethal manifestations and further spread to the community. This 4-part review covers the epidemiology, pathogenesis, and management of the disease, including new treatment options. The third part of the review will focus on the clinical management of MRSA infection.
Subject(s)
Anti-Bacterial Agents/therapeutic use , Community-Acquired Infections/drug therapy , Methicillin Resistance , Staphylococcal Skin Infections/drug therapy , Acetamides/therapeutic use , Algorithms , Clindamycin/therapeutic use , Humans , Linezolid , Oxazolidinones/therapeutic use , Staphylococcus aureus/drug effects , Tetracycline/therapeutic use , Trimethoprim, Sulfamethoxazole Drug Combination/therapeutic use , Vancomycin/therapeutic useABSTRACT
Methicillin-resistant Staphylococcus aureus (MRSA) is increasingly becoming a major source of systemic infection in the community and healthcare settings. The disease is responsible for deaths among individuals without known risk factors and presents a therapeutic challenge for clinicians because of the bacteria's complex epidemiology and mechanisms of antibiotic resistance. Furthermore, the skin and soft tissue are the most commonly infected organs. Consequently, it is necessary for the dermatologist to have an understanding of the management of the condition to prevent lethal manifestations and further spread to the community. This 4-part review covers the epidemiology, pathogenesis, and management of the disease, including new treatment options. The fourth part of the review will focus on additional therapeutic considerations in the management of MRSA infection.
Subject(s)
Anti-Bacterial Agents/therapeutic use , Community-Acquired Infections/drug therapy , Immunoglobulins, Intravenous/therapeutic use , Methicillin Resistance , Staphylococcal Skin Infections/drug therapy , Administration, Topical , Anti-Bacterial Agents/administration & dosage , Antisepsis/methods , Humans , Nasal Cavity/microbiology , Staphylococcal Skin Infections/prevention & control , Staphylococcus aureus/drug effectsABSTRACT
Methicillin-resistant Staphylococcus aureus (MRSA) is increasingly becoming a major source of systemic infection in the community and healthcare settings. The disease is responsible for deaths among individuals without known risk factors and presents a therapeutic challenge for clinicians because of the bacteria's complex epidemiology and mechanisms of antibiotic resistance. Furthermore, the skin and soft tissue are the most commonly infected organs. Consequently, it is necessary for the dermatologist to have an understanding of the management of the condition to prevent lethal manifestations and further spread to the community. This 4-part review covers the epidemiology, pathogenesis, and management of the disease, including new treatment options. The first part of the review will focus on the epidemiology of MRSA infection.
Subject(s)
Community-Acquired Infections/epidemiology , Methicillin Resistance , Staphylococcal Skin Infections/epidemiology , Staphylococcus aureus , Carrier State , Humans , Risk FactorsABSTRACT
Methicillin-resistant Staphylococcus aureus (MRSA) is increasingly becoming a major source of systemic infection in the community and healthcare settings. The disease is responsible for deaths among individuals without known risk factors and presents a therapeutic challenge for clinicians because of the bacteria's complex epidemiology and mechanisms of antibiotic resistance. Furthermore, the skin and soft tissue are the most commonly infected organs. Consequently, it is necessary for the dermatologist to have an understanding of the management of the condition to prevent lethal manifestations and further spread to the community. This 4-part review covers the epidemiology, pathogenesis, and management of the disease, including new treatment options. The second part of the review will focus on the pathogenesis and cutaneous manifestations of MRSA infection.
Subject(s)
Community-Acquired Infections/diagnosis , Methicillin Resistance , Staphylococcal Skin Infections/diagnosis , Staphylococcus aureus , Humans , Staphylococcus aureus/genetics , Staphylococcus aureus/pathogenicity , VirulenceABSTRACT
We report a case of an immunocompetent man with a 4-year history of persistent pruritic lesions along the long axis of his forearm. The symptoms began 3 years after the patient immigrated to New York from Mexico. A histopathologic evaluation demonstrated primary cutaneous nocardiosis. This rare case of Nocardia brasiliensis infection in a nontropical area raises the possibility that the incubation period for Nocardia may be longer than previously believed. Alternatively, cutaneous nocardiosis may occur in a wider geographic area than previously recognized.
