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1.
West Indian Med J ; 53(3): 147-9, 2004 Jun.
Article in English | MEDLINE | ID: mdl-15352741

ABSTRACT

Malondialdehyde, a lipid peroxide, may be used as an indicator of oxidative stress. This study investigated the oxidative stress hypothesis in patients infected with Plasmodium vivax. Serum malondialdehyde (MDA) concentration activity was measured in 87 patients. Scores were obtained for the patients and 60 seronegative healthy controls matched for age and gender. The difference between MDA levels of patients infected with Plasmodium vivax and the control group was statistically significant both for females (p < 0.001) and males (p < 0.001). In the patient and control group, no correlation was found between age and malondialdehyde levels (p > 0.05) in both females and males. In addition, no significant correlation could be found between MDA levels of both females and males for patients and control group (p > 0.05). MDA levels were increased in the patients infected with Plasmodium vivax.


Subject(s)
Malaria/blood , Malondialdehyde/blood , Plasmodium vivax/isolation & purification , Adolescent , Adult , Aged , Animals , Case-Control Studies , Female , Humans , Lipid Peroxidation/physiology , Male , Middle Aged , Oxidative Stress/physiology
2.
West Indian med. j ; West Indian med. j;53(3): 147-149, Jun. 2004.
Article in English | LILACS | ID: lil-410476

ABSTRACT

Malondialdehyde, a lipid peroxide, may be used as an indicator of oxidative stress. This study investigated the oxidative stress hypothesis in patients infected with Plasmodium vivax. Serum malondialdehyde (MDA) concentration activity was measured in 87 patients. Scores were obtained for the patients and 60 seronegative healthy controls matched for age and gender. The difference between MDA levels of patients infected with Plasmodium vivax and the control group was statistically significant both for females (p < 0.001) and males (p < 0.001). In the patient and control group, no correlation was found between age and malondialdehyde levels (p > 0.05) in both females and males. In addition, no significant correlation could be found between MDA levels of both females and males for patients and control group (p > 0.05). MDA levels were increased in the patients infected with Plasmodium vivax


Subject(s)
Humans , Animals , Male , Female , Adolescent , Adult , Middle Aged , Malondialdehyde/blood , Malaria/blood , Plasmodium vivax/isolation & purification , Oxidative Stress/physiology , Case-Control Studies , Lipid Peroxidation/physiology
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