1.
South Med J
; 69(10): 1372-4, 1976 Oct.
Article
in English
| MEDLINE
| ID: mdl-982119
ABSTRACT
A 70-year-old woman with polymyositis was treated with three different immunosuppressive drugs. Her condition deteriorated over a three-month period until she became totally helpness. She then made a dramatic improvement when large doses of vitamin E (d, alpha-tocopheryl acetate) were administered. Current knowledge regarding the nature of polymyositis and the rationale for using vitamin E to treat it are discussed.
Subject(s)
Myositis/drug therapy , Vitamin E/therapeutic use , Aged , Aspartate Aminotransferases/blood , Creatine Kinase/blood , Dose-Response Relationship, Drug , Electromyography , Female , Fructose-Bisphosphate Aldolase/blood , Humans , Immunosuppression Therapy , L-Lactate Dehydrogenase/blood , Muscular Atrophy/drug therapy , Myositis/enzymology , Prednisone/therapeutic use , Vitamin E/administration & dosage
2.