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1.
Isatuximab-VRd quadruplet shows promise in transplant-ineligible NDMM.
Killock, David.
Nat Rev Clin Oncol ; 2024 Jun 18.
Article in English | MEDLINE | ID: mdl-38890555
2.
Vimseltinib improves outcomes in tenosynovial giant cell tumour.
Killock, David.
Nat Rev Clin Oncol ; 2024 Jun 24.
Article in English | MEDLINE | ID: mdl-38914834
3.
NICHE-2 validates the efficacy of neoadjuvant ICIs in dMMR colon cancer.
Killock, David.
Nat Rev Clin Oncol ; 2024 Jun 21.
Article in English | MEDLINE | ID: mdl-38907078
4.
Adding ibrutinib to frontline therapy improves outcomes in transplant-eligible patients with MCL.
Killock, David.
Nat Rev Clin Oncol ; 21(7): 483, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38789564

Subject(s)
Adenine , Antineoplastic Combined Chemotherapy Protocols , Lymphoma, Mantle-Cell , Piperidines , Pyrazoles , Pyrimidines , Humans , Piperidines/therapeutic use , Adenine/analogs & derivatives , Adenine/therapeutic use , Pyrazoles/therapeutic use , Pyrimidines/therapeutic use , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Lymphoma, Mantle-Cell/drug therapy , Treatment Outcome , Hematopoietic Stem Cell Transplantation
5.
ALND can be safely omitted for patients with sentinel-node macrometastases.
Killock, David.
Nat Rev Clin Oncol ; 21(6): 402, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38637648

Subject(s)
Lymphatic Metastasis , Sentinel Lymph Node Biopsy , Sentinel Lymph Node , Humans , Sentinel Lymph Node/pathology , Sentinel Lymph Node/surgery , Lymph Node Excision/methods , Breast Neoplasms/pathology , Female
6.
FIRSTMAPPP prospectively charts the efficacy of sunitinib for phaeochromocytoma and paraganglioma.
Killock, David.
Nat Rev Clin Oncol ; 21(5): 335, 2024 May.
Article in English | MEDLINE | ID: mdl-38459158

Subject(s)
Adrenal Gland Neoplasms , Paraganglioma , Pheochromocytoma , Sunitinib , Humans , Sunitinib/therapeutic use , Pheochromocytoma/drug therapy , Paraganglioma/drug therapy , Adrenal Gland Neoplasms/drug therapy , Prospective Studies , Antineoplastic Agents/therapeutic use , Treatment Outcome
7.
IL-13Rα2-targeted CAR T cells show promise in patients with recurrent high-grade gliomas.
Killock, David.
Nat Rev Clin Oncol ; 21(5): 335, 2024 May.
Article in English | MEDLINE | ID: mdl-38514882

Subject(s)
Brain Neoplasms , Glioma , Immunotherapy, Adoptive , Interleukin-13 Receptor alpha2 Subunit , Receptors, Chimeric Antigen , Humans , Glioma/immunology , Glioma/pathology , Glioma/therapy , Immunotherapy, Adoptive/methods , Receptors, Chimeric Antigen/immunology , Interleukin-13 Receptor alpha2 Subunit/genetics , Brain Neoplasms/immunology , Brain Neoplasms/pathology , Brain Neoplasms/therapy , Neoplasm Recurrence, Local/immunology , Neoplasm Recurrence, Local/pathology , T-Lymphocytes/immunology
8.
Adjuvant chemotherapy improves OS in UTUC.
Killock, David.
Nat Rev Clin Oncol ; 21(4): 251, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38388707

Subject(s)
Carcinoma, Transitional Cell , Kidney Neoplasms , Urologic Neoplasms , Humans , Urologic Neoplasms/drug therapy , Kidney Neoplasms/drug therapy , Chemotherapy, Adjuvant , Carcinoma, Transitional Cell/drug therapy
9.
Personalized neoantigen mRNA vaccine mitigates melanoma recurrence.
Killock, David.
Nat Rev Clin Oncol ; 21(3): 168, 2024 Mar.
Article in English | MEDLINE | ID: mdl-38302646

Subject(s)
Cancer Vaccines , Melanoma , Humans , Melanoma/genetics , mRNA Vaccines , Antigens, Neoplasm/genetics , Lymphocytes, Tumor-Infiltrating , Cancer Vaccines/therapeutic use , Immunotherapy
10.
From CHRYSALIS to PAPILLON: the metamorphosis of amivantamab into frontline therapy for NSCLC.
Killock, David.
Nat Rev Clin Oncol ; 21(1): 5, 2024 Jan.
Article in English | MEDLINE | ID: mdl-37923902

Subject(s)
Antibodies, Bispecific , Carcinoma, Non-Small-Cell Lung , Lung Neoplasms , Animals , Humans , Pupa , Carcinoma, Non-Small-Cell Lung/drug therapy , Lung Neoplasms/drug therapy
11.
From the ESMO Congress 2023.
Killock, David.
Nat Rev Clin Oncol ; 21(1): 3, 2024 Jan.
Article in English | MEDLINE | ID: mdl-37907722

Subject(s)
Medical Oncology , Neoplasms , Humans , Neoplasms/genetics , Neoplasms/therapy
12.
PERSEUS triumphs - efficacy of daratumumab confirmed in transplant-eligible NDMM.
Killock, David.
Nat Rev Clin Oncol ; 21(3): 167, 2024 Mar.
Article in English | MEDLINE | ID: mdl-38123694

Subject(s)
Multiple Myeloma , Humans , Multiple Myeloma/drug therapy , Antibodies, Monoclonal/therapeutic use , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Bortezomib/therapeutic use
13.
Irradiation of asymptomatic bone metastases improves outcomes.
Killock, David.
Nat Rev Clin Oncol ; 20(12): 817, 2023 Dec.
Article in English | MEDLINE | ID: mdl-37803132

Subject(s)
Bone Neoplasms , Humans , Bone Neoplasms/radiotherapy , Palliative Care
14.
Novel ICI-TKI combination improves HCC outcomes.
Killock, David.
Nat Rev Clin Oncol ; 20(11): 733, 2023 11.
Article in English | MEDLINE | ID: mdl-37563429

Subject(s)
Carcinoma, Hepatocellular , Liver Neoplasms , Humans , Carcinoma, Hepatocellular/drug therapy , Liver Neoplasms/drug therapy
15.
Platinum-ineligible: atezolizumab preferable.
Killock, David.
Nat Rev Clin Oncol ; 20(10): 661, 2023 10.
Article in English | MEDLINE | ID: mdl-37479811

Subject(s)
Antibodies, Monoclonal, Humanized , Platinum , Humans , Antibodies, Monoclonal, Humanized/adverse effects
16.
Adjuvant nivolumab shows promise in MCC.
Killock, David.
Nat Rev Clin Oncol ; 20(11): 734, 2023 11.
Article in English | MEDLINE | ID: mdl-37507497

Subject(s)
Antineoplastic Agents, Immunological , Melanoma , Skin Neoplasms , Humans , Nivolumab/therapeutic use , Melanoma/drug therapy , Antineoplastic Agents, Immunological/therapeutic use , Skin Neoplasms/drug therapy , Ipilimumab/therapeutic use
17.
New anti-angiogenic option for mCRC.
Killock, David.
Nat Rev Clin Oncol ; 20(9): 579, 2023 09.
Article in English | MEDLINE | ID: mdl-37386147

Subject(s)
Angiogenesis Inhibitors , Colorectal Neoplasms , Humans , Angiogenesis Inhibitors/therapeutic use , Colorectal Neoplasms/drug therapy , Colorectal Neoplasms/genetics
18.
Newly diagnosed AML: quizartinib improves OS.
Killock, David.
Nat Rev Clin Oncol ; 20(8): 504, 2023 08.
Article in English | MEDLINE | ID: mdl-37253972

Subject(s)
Antineoplastic Agents , Leukemia, Myeloid, Acute , Humans , Antineoplastic Agents/therapeutic use , Benzothiazoles/therapeutic use , Phenylurea Compounds/therapeutic use , Leukemia, Myeloid, Acute/drug therapy
19.
HSCT prolongs remission of high-risk CTCLs.
Killock, David.
Nat Rev Clin Oncol ; 20(7): 426, 2023 07.
Article in English | MEDLINE | ID: mdl-37147418

Subject(s)
Hematopoietic Stem Cell Transplantation , Leukemia, Myeloid, Acute , Humans , Treatment Outcome , Transplantation, Homologous , Remission Induction , Disease-Free Survival
20.
Biliary tract cancer: frontline pembrolizumab hits KEYNOTE.
Killock, David.
Nat Rev Clin Oncol ; 20(7): 425, 2023 07.
Article in English | MEDLINE | ID: mdl-37106149

Subject(s)
Biliary Tract Neoplasms , Carcinoma, Non-Small-Cell Lung , Lung Neoplasms , Humans , Lung Neoplasms/drug therapy , Carcinoma, Non-Small-Cell Lung/drug therapy , Antibodies, Monoclonal, Humanized/adverse effects , Biliary Tract Neoplasms/drug therapy , Antineoplastic Combined Chemotherapy Protocols
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