Subject(s)
Cornea/physiopathology , Lipids/physiology , Tears/physiology , Biomechanical Phenomena , HumansSubject(s)
Blinking , Keratoconjunctivitis Sicca/etiology , Keratoconjunctivitis/etiology , Humans , Time FactorsSubject(s)
Corneal Injuries , Lasers/adverse effects , Regeneration , Animals , Cornea/pathology , Endothelium/pathology , Microscopy, Electron , RabbitsSubject(s)
Contact Lenses, Extended-Wear , Contact Lenses, Hydrophilic , Cornea/enzymology , Animals , Blood Glucose/metabolism , Epithelium/enzymology , Glyceraldehyde-3-Phosphate Dehydrogenases/metabolism , Hexokinase/metabolism , L-Lactate Dehydrogenase/metabolism , Pyruvates/metabolism , Pyruvic Acid , Rabbits , Regeneration , Triose-Phosphate Isomerase/metabolismABSTRACT
This paper describes the alterations in the structure of the tear film and its composition, which can lead to the dry eye syndrome. An attempt has been made to differentiate the individual components of these syndromes and Vogt's method is described as a further aid to diagnosis.
Subject(s)
Tears/physiology , Xerophthalmia/physiopathology , Blinking , Humans , Lipids/analysis , Mucins/analysis , Optics and Photonics , Surface Properties , Tears/analysis , Xerophthalmia/metabolismSubject(s)
Anesthetics/pharmacology , Blinking/drug effects , Tears , Humans , Infrared Rays , Physiology/instrumentation , Physiology/methods , Time FactorsSubject(s)
Cornea/cytology , Microscopy/instrumentation , Video Recording , Animals , Endothelium , SwineABSTRACT
A reported on 27 eyes (25 patients) which were fitted with soft permanent lenses following penetrating keratoplasty. The eyes were divided into three groups, according to the nature of the epithelial damage caused by the lens: 1) mechanical damage; 2) primary damage to the endothelium with secondary epithelial resistance. In 52% of the cases superficial neovascularization occurred, but this did not lead to serious complications. In the first and second groups, infiltrates were only seen after longterm use. The highest rate of complications, with infiltrates occurring relatively early and with liquefaction, was observed in the third group. In the first group the permanent lens led to lasting stabilization of the condition with a relatively low risk. In the second group the lens brought freedom from complaints with complications occurring only after 1-2 years. In the third group it was found that complications with negative courses may arise after only a short time.
Subject(s)
Contact Lenses, Hydrophilic , Corneal Transplantation , Contact Lenses, Hydrophilic/adverse effects , Cornea/blood supply , Corneal Diseases/pathology , Corneal Diseases/surgery , Humans , Neovascularization, PathologicSubject(s)
Organ Preservation , Tissue Preservation , Vitreous Body/physiology , Animals , Biomechanical Phenomena , Humans , In Vitro Techniques , Microspheres , Sodium Chloride , SwineABSTRACT
The examination of tear film by specular microscopy enables various phenomena to be observed in normal and irritated eyes. In cases of dry eye syndrome some differentiations are possible.
