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1.
Liver Int ; 42(7): 1648-1657, 2022 07.
Article in English | MEDLINE | ID: mdl-35445513

ABSTRACT

BACKGROUND AND AIMS: We assessed the imaging outcomes of Liver Imaging Reporting and Data System (LI-RADS) v2018 categories in prospective hepatocellular carcinoma (HCC) surveillance cohort and determined imaging features significantly predictive of progression to a malignant LI-RADS category. METHODS: The imaging outcomes of 120 patients (162 observations) prospectively enrolled between November 2011 and August 2012 were analysed according to LI-RADS v2018. Cumulative incidences for progression to a malignant category (LR-5 or LR-M) and LR-4 or higher were calculated for each baseline category and compared using log-rank tests. Clinical variables and imaging features significantly predictive of progression to a malignant category were evaluated using Cox proportional hazards modelling. RESULTS: The 162 observations were initially categorized into 60 LR-2, 75 LR-3 and 27 LR-4. For LR-4 observations, the 1-year, 3-year and 5-year cumulative incidences of progression to a malignant category were 18.5% (95% confidence interval, 6.6-35.2%), 43.0% (23.1-61.5%) and 52.5% (25.9-73.5%), which were significantly higher than those of LR-2 and LR-3 (p < .001). For LR-3, the 1-year, 3-year and 5-year cumulative incidences of progression to LR-4 or higher were 4.1% (1.1-10.4%), 13.9% (6.7-23.6%) and 23.1% (12.7-35.4%), which were significantly higher than that of LR-2 (p  = .009). In multivariable analysis, size ≥1.0 cm (hazard ratio [HR] = 2.58, 1.04-6.40) and nonrim arterial-phase hyperenhancement (HR = 2.45, 1.11-5.42) were significantly independently associated with progression to a malignant category. CONCLUSION: Long-term imaging outcomes differed significantly according to LI-RADS category. Size ≥1.0 cm and nonrim arterial-phase hyperenhancement were imaging features significantly predictive of progression to a malignant category.


Subject(s)
Carcinoma, Hepatocellular , Liver Neoplasms , Carcinoma, Hepatocellular/diagnostic imaging , Carcinoma, Hepatocellular/pathology , Contrast Media , Humans , Liver Neoplasms/diagnostic imaging , Liver Neoplasms/pathology , Magnetic Resonance Imaging , Prospective Studies , Retrospective Studies , Sensitivity and Specificity
2.
Interv Neuroradiol ; 20(5): 609-13, 2014 Oct 31.
Article in English | MEDLINE | ID: mdl-25363264

ABSTRACT

We describe a rare case of aneurysmal bone cysts (ABCs) that occurred in the petrous portion of the temporal bone. The ABCs were treated with preoperative embolization and complete removal of the mass from the adjacent tissue. The technical details suggest that preoperative embolization is a good treatment option for ABCs.


Subject(s)
Bone Cysts, Aneurysmal/surgery , Embolization, Therapeutic/methods , Neurosurgical Procedures/methods , Temporal Bone/surgery , Adolescent , Bone Cysts, Aneurysmal/diagnostic imaging , Female , Humans , Magnetic Resonance Imaging , Preoperative Care , Temporal Bone/diagnostic imaging , Tomography, X-Ray Computed
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