ABSTRACT
This study investigates and compares the microstructure, biocompatibility, and tribological properties of two different Ti-based composites, Ti-10W and Ti-7.5TiC-7.5W, with those of pure Ti for their potential use in biomedical applications. In particular, cold and hot isostatic-pressing and arc-melting methods were utilized and compared for the microstructure of the composites. Nano-scratch measurements and pin-on-disk wear tests were employed to understand their tribological behavior. As compared to pure Ti, Ti-10W and Ti-7.5TiC-7.5W showed significantly improved nano-scratch resistance (by 85 and 77%, respectively) and wear resistance (by 64 and 66%, respectively), in good agreement with hardness measurements. For biocompatibility examination, both microculture tetrazolium test (MTT) and water soluble tetrazolium (WST-1) test were used to quantify the cell viability of human osteoblasts and mouse fibroblasts on the materials. Both of the Ti-based composites showed acceptable biocompatibility in comparison with the pure Ti control.
Subject(s)
Alloys/chemistry , Biocompatible Materials/chemistry , Materials Testing , Titanium/chemistry , Tungsten/chemistry , Animals , Biocompatible Materials/toxicity , Cell Line , Cell Survival/drug effects , Humans , Mice , Osteoblasts/cytology , Osteoblasts/drug effects , Surface PropertiesABSTRACT
Chondromyxoid fibroma is an uncommon benign cartilaginous tumor of the bone. It occurs most frequently in the metaphysis of long tubular bones, and an epiphyseal location is exceedingly rare. We present here an unusual case of a chondromyxoid fibroma that occurred in the epiphysis of the proximal tibia with an open growth plate. MR imaging findings of this tumor, which has, to the best of our knowledge, never been described in an epiphyseal location, makes the present case unique.
Subject(s)
Bone Neoplasms/diagnosis , Chondroma/diagnosis , Fibroma/diagnosis , Tibia , Adolescent , Epiphyses , Humans , Magnetic Resonance Imaging , MaleABSTRACT
We report a case of focal hematopoietic hyperplasia in the rib of a 24-year-old woman. This is only the fourth case to be reported in the English literature, all of which have involved the rib. Radiologically they all manifested as an expansive and radiolucent lesion and contained ill-defined areas of increased density or calcification. Histologically, all have been characterized by mixed areas of hypercellular marrow and fatty marrow. The lesion is considered a form of pseudotumor. Treatment in our case was by wide marginal excision of the rib.
