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1.
Front Psychol ; 14: 1259218, 2023.
Article in English | MEDLINE | ID: mdl-37901086

ABSTRACT

This study examined the relationship between the transformational leadership of PE instructors and students' satisfaction in an online PE class. In particular, it aimed to investigate whether the PE instructors' transformational leadership behaviors could predict students' satisfaction toward the class, their PE teacher, and their health and fitness. Furthermore, this study explored these relationships in male and female students. A total of 448 university students (male = 228; female = 220) between the ages of 18 and 22 participated in the study. The results revealed a positive relationship between the transformational leadership behaviors of PE instructors and students' satisfaction with online PE classes. Moreover, male and female students' satisfaction with the teaching of their PE instructor, feelings of fun and enjoyment, and perception of improved health and fitness in their online PE classes varied greatly as they perceived specific behaviors of transformational leadership from their PE instructors. These findings demonstrate that PE instructors play an important role as (online) classroom leaders in enhancing students' satisfaction with online learning. Therefore, PE instructors should be mindful to demonstrate transformational leadership to improve their effectiveness when conducting online classes.

2.
Front Psychiatry ; 14: 1175974, 2023.
Article in English | MEDLINE | ID: mdl-37484683

ABSTRACT

Introduction: Investigation on the association between attention deficit hyperactivity disorder (ADHD) and primary reflexes is in the initial stage, with considerable differences in the findings. This study evaluated the association between ADHD and primitive reflexes using systematic review and meta-analysis. Methods: Data were obtained from PubMed, Cochrane Library, Web of Science, EBSCO (Medical Literature Analysis and Retrieval System Online, American Psychological Association Psyclnfo, and Education Resources Information Center), Embase, Scopus, and ProQuest. Articles were searched from the date of inception of the respective databases to January 01, 2023, and StataCorp Stata (version 15) was used for the analysis. Results: Four articles with 229 samples were included in the meta-analysis. Results showed a significant positive and moderate correlation between ADHD and primitive reflexes, particularly asymmetric tonic neck reflex: summary r value = 0.48, 95% CI = 0.27-0.64; symmetric tonic neck reflex: summary r value = 0.39, 95% CI = 0.25-0.52. Overall, findings from the sub-group analysis indicate that the behavioral problem measuring tool (Conners' scale), sex, and primitive reflex test could significantly moderate the relationships between ADHD and ATNR and STNR primitive reflexes. Conclusion: ADHD symptoms in children are closely related to the non-integration of (a)symmetric tonic neck primitive reflexes. Longitudinal or experimental studies should be conducted to reveal the causal relationship between ADHD and primitive reflexes in the future.

3.
Front Psychol ; 14: 1172897, 2023.
Article in English | MEDLINE | ID: mdl-36968688

ABSTRACT

[This corrects the article DOI: 10.3389/fpsyg.2023.1135243.].

4.
Front Psychol ; 14: 1135243, 2023.
Article in English | MEDLINE | ID: mdl-36844359

ABSTRACT

This study examined published articles concerning sports leadership within the sport psychology domain over the last 30 years using bibliometric analysis that centered on the written content of the publications as unit of analysis in order to explore the intellectual base, particularly the structural relationships among relevant research components about coach leadership. Leximancer version 5.0 (Leximancer Pty Ltd.) was used to extract data from 100 sports leadership-related articles from four sport psychology journals. Overall, the most relevant concepts generated were coaches (100%) and athletes (59%), followed by study, sport, support, and motivation, and behaviors. Also, relevant concepts produced for each journal were quite similar which included coaches, athletes, behaviors, study, support and team. Further, publications related to coach leadership have shown a steady growth rate since 1990 with 76% of all published articles were conducted via quantitative research method. Finally, United States, Canada, the United Kingdom, and Belgium were the top countries involved in the area of coach leadership. Coach leadership studies generally focus on behaviors and perceptions related to the coach and relationships between leadership and psychological outcomes. Each journal has a similar but distinct rationale when publishing papers about coach leadership. Bibliometric analysis can be applied as an alternative methodology to summarize large volumes of relevant data in order to map the current knowledge as well as identify potential future research directions.

5.
Article in English | MEDLINE | ID: mdl-36673793

ABSTRACT

This systematic review and meta-analysis aimed to systematically evaluate the effect of physical activity (PA) on inhibitory function in children with ADHD. Experimental studies on the effect of PA on the inhibitory function of children with ADHD were retrieved. The data were obtained from PubMed, The Cochrane Library, Web of Science, EBSCO (MEDLINE, APA Psyclnfo, ERIC), Embase, Scopus, and ProQuest. The search period was from the date of inception of the respective databases to 4 May 2022, and Reviewer Manager software (version 5.3) was used for analysis. Eleven articles and 713 samples were included in the meta-analysis. Results revealed that PA can significantly improve the inhibitory function of children with ADHD (SMD = 0.78, 95% CI: 0.45−1.10, p < 0.001). Subgroup analysis showed that the effectiveness of PA as an intervention in improving the inhibitory function of children with ADHD was moderated by the frequency, intensity, duration, type, and length of intervention. Based on the findings, PA can effectively improve interference suppression inhibitory function in children with ADHD. Longitudinal open-skill exercise for 60 min or more, two times/week has the best effect on improving inhibitory function in children with ADHD.


Subject(s)
Attention Deficit Disorder with Hyperactivity , Humans , Child , Exercise
6.
Front Psychol ; 13: 915391, 2022.
Article in English | MEDLINE | ID: mdl-35800950

ABSTRACT

This study meta-analyzed the relationships between coach transformational leadership and player satisfaction and commitment. We also examined the potential moderating effect of player gender on these relationships. In total, 182 effect sizes were obtained from 26 studies comprised of 6,715 participants. The analyses revealed that the overall direct effect of transformational leadership was moderate on both athletic satisfaction and exercise commitment. The effect of charismatic construct of transformational leadership was moderate on athletic satisfaction as well as exercise commitment. Finally, player gender was found to moderate the effects of the relationship between transformational leadership and athletic satisfaction and exercise commitment of players. Specifically, female players' satisfaction and commitment were more positively affected by transformational leadership compared with their male counterparts. Our findings suggests that effective leadership in sports is dependent on the interaction among leadership behaviors of the coach, personal characteristics of the players, and situational factors and highlights the importance of transformational leadership as an important requirement for creating a more positive and sustainable sports environment.

7.
Article in English | MEDLINE | ID: mdl-35805846

ABSTRACT

Leaders play a significant role in organizations and their leadership behaviors can either enhance or undermine the well-being of their employees. This study aimed to meta-analyze the relationship between transformational leadership and well-being in the service industry, and how employees' gender and service sector moderated the strength of this relationship. This study used a convergent mixed-method approach. PubMed, MEDLINE, Google Scholar, AMED, and Scopus electronic databases were utilized to search for relevant studies. Textual data were analyzed using a text data-mining technique (Leximancer) to determine the relevant themes and concepts. Statistical data were examined through a comprehensive meta-analysis to determine their effect sizes. The qualitative results outline the major themes that emerged: leadership, well-being, and health. The quantitative findings revealed that the perceived well-being of male employees and those working outside of the health-care service sector was positively higher when employees' leaders showed transformational leadership. In general, the findings from the qualitative and quantitative data converge. The findings confirm the positive relationship between transformational leadership and employee well-being. This study also highlights the applicability of a convergent mixed-method approach as a useful methodological strategy when analyzing both lexical and statistical data.


Subject(s)
Industry , Leadership , Humans , Male
8.
BMC Oral Health ; 22(1): 255, 2022 06 25.
Article in English | MEDLINE | ID: mdl-35752793

ABSTRACT

OBJECTIVES: This study aimed to develop a new chewing problem directory (CPD) and validate it with oral health indicators such as total occlusion force, number of natural and rehabilitated teeth (NRT), NRT posterior, natural teeth, natural teeth posterior, and dental status among Korean elders. BACKGROUND: Chewing problem is the main oral health problem in elders. However, there has been no validated tool using both subjective and objective assessment of chewing problem. SUBJECTS AND METHODS: A total of 537 participants aged 65 years or more were randomly assigned into 2 subsamples: developing sample (n = 260) for developing and internally validating the new CPD as the 1st stage and confirmation sample (n = 277) for confirming validation of CPD as the 2nd stage. CPD was developed using three subjective questionnaires (general eating, chewing nuts, and chewing meat problem) and objective NRT. Periodontitis, age, sex, education, smoking, alcohol drinking, metabolic syndrome, and frailty were considered as confounders. Following the development of CPD, CPD was validated using multiple multivariable logistic regression after controlling for confounders in confirmation sample and total sample. RESULTS: The Cronbach's alpha value for three subjective questionnaires of CPD was 0.87. Among oral health indicators, NRT (0-28) showed the highest impact association with subjective chewing problem score (partial r = - 0.276). The chewing problem from the new CPD was associated with all items of oral health indicators. The prevalence of chewing problems by CPD was 57.7% in developing sample. Elders with NRT ≤ 24, compared with those with NRT ≥ 25, showed the highest impact on chewing problems by new CPD (Odds Ratio = 7.3 in the confirmation sample and 5.04 in the total sample, p < 0.05) among oral health indicators. CONCLUSION: This new CPD was developed as a valid tool to evaluate the chewing problem for Korean elders in dental clinics and community-based settings.


Subject(s)
Mastication , Mouth, Edentulous , Oral Health , Aged , Humans , Patient Acuity , Republic of Korea/epidemiology , Surveys and Questionnaires
10.
BMC Oral Health ; 22(1): 168, 2022 05 06.
Article in English | MEDLINE | ID: mdl-35524199

ABSTRACT

OBJECTIVE: To evaluate the association between oral health-related quality of life (OHRQoL) and oral health indicators including dental status, total occlusion force (TOF), number of natural and rehabilitated teeth (NRT), number of natural teeth (NT), and to explore the effect modification on the association by gender among Korean elders. METHODS: A total of 675 participants aged 65 or above recruited by a cluster-based stratified random sampling were included in this cross-sectional study. The 14-items Korean version of the Oral Health Impact Profile (OHIP) was used to measure OHRQoL. The responses about OHIP were dichotomized by the cut-off point of 'fairly often' to determine the 'poor' versus 'fair' OHRQoL. Age, gender, education level, alcohol drinking, smoking, metabolic syndrome, frailty, and periodontitis were considered as confounders. Multiple multivariable logistic regression analyses were applied to assess the adjusted association between oral health indicators and OHRQoL. Gender stratified analysis was also applied to explore the effect modification of the association. RESULTS: The prevalence of poor OHRQoL was 43.0%, which was higher in women, less-educated elders, alcohol non-drinkers and frailty elders (p < 0.05). Elders with poor OHRQoL also showed lower values of oral health indicators than elders with fair OHRQoL (p < 0.05). Those with NRT ≤ 24, NT ≤ 14, and TOF < 330 N increased the risk of poor OHRQoL by 2.3 times (OR = 2.26, confidence interval [CI] 1.54-3.31), 1.5 times (OR = 1.45, CI 1.02-2.07), and 1.5 times (OR = 1.47, CI 1.06-2.04), respectively. In women, the association of NRT ≤ 24 with poor OHRQoL increased from OR of 2.3 to OR of 2.4, while, in men, the association of TOF < 330 N with poor OHRQoL increased from OR of 1.5 to OR of 3.2. CONCLUSION: Oral health indicators consisting of TOF, NRT, and NT were independently associated with poor OHRQoL among Korean elders. Gender modified the association of TOF and NRT. Preventive and/or curative management for keeping natural teeth and the rehabilitation of missing teeth to recover the occlusal force may be essential for reducing poor OHRQoL.


Subject(s)
Frailty , Mouth, Edentulous , Aged , Cross-Sectional Studies , Female , Humans , Male , Oral Health , Quality of Life , Republic of Korea/epidemiology , Surveys and Questionnaires
11.
BMC Oral Health ; 21(1): 571, 2021 11 08.
Article in English | MEDLINE | ID: mdl-34749709

ABSTRACT

BACKGROUND: This study aimed to investigate the distribution of objective total occlusal force (TOF) and its association with dental health indicators: dental status, number of natural teeth (NT), natural and rehabilitated teeth, natural posterior teeth (NT-Post), and natural and rehabilitated posterior teeth among Korean elders after controlling for various confounders encompassing socio-demographic factors, behavioral factors and health/oral health factors. METHODS: This cross-sectional study recruited 551 elders from the Sungbook-Gu health education cohort. TOF was measured using Prescale II as an outcome variable. Dental health indicators assessed by dentists were the main explanatory variables. Analysis of covariance and multivariable linear regression models were applied to evaluate the adjusted association of dental health indicators with TOF. Gender and age group stratified analyses were also applied. RESULT: TOF was higher in dentate elders than denture wearers in males and younger elders. The adjusted mean of TOF and standard error was 464.24 ± 17.15 N for dentate elders, 297.15 ± 28.85 N for partial denture wearers, 280.42 ± 47.71 N for complete denture wearers. Among all dental health indicators, NT-Post showed the highest association with TOF (partial r = 0.330, p < 0.001, R2 = 0.15), followed by NT (partial r = 0.329, p < 0.001, R2 = 0.16). Older elders highlighted the association of NT (partial r = 0.37, p < 0.001, R2 = 0.18). Males decreased the association of NT (partial r = 0.30, p < 0.001, R2 = 0.20) and NT-Post (partial r = 0.29, p < 0.001, R2 = 0.20). CONCLUSION: TOF was significantly associated with dental health indicators, and its association was modified by sex and age group.


Subject(s)
Bite Force , Mouth, Edentulous , Aged , Cross-Sectional Studies , Denture, Complete , Humans , Male , Republic of Korea/epidemiology
12.
BMC Oral Health ; 21(1): 388, 2021 08 09.
Article in English | MEDLINE | ID: mdl-34372836

ABSTRACT

BACKGROUND: Periodontitis is one of major oral diseases, which has no consensus on early screening tool. This study aimed to compare the association and screening ability of S100A8 and S100A9 in saliva, blood and gingival crevicular fluid (GCF) for periodontitis status. METHODS: We recruited 149 community Korean adults, 50 no or initial periodontitis (NIPERIO) and 99 established periodontitis (PERIO). Using clinical attachment loss and a panoramic radiograph, stage II-IV of new classification of periodontitis proposed at 2018 was considered cases as PERIO. Enzyme linked immunosorbent assay kit was used to quantify S100A8 and S100A9. T-test, analysis of covariance, Mann-Whitney test and correlation analysis were applied to compare the relationship of S100A8 and S100A9 in saliva, blood, and GCF for periodontitis. Receiver operating characteristic curve was applied for screening ability. RESULTS: Among S100A8 and S100A9 in saliva, blood and GCF, S100A8 in saliva was significantly higher in PERIO than in NIPERIO (p < 0.05). However, S100A8 and S100A9 in GCF were higher in NIPERIO (p < 0.05). The screening ability of salivary S100A8 was 75% for PERIO, while that of GCF S100A8 was 74% for NIPERIO. Salivary S100A8 was positively correlated to blood S100A8 (p < 0.05). CONCLUSION: Salivary S100A8 could be a potential diagnostic marker for established periodontitis and be useful for screening established periodontitis.


Subject(s)
Gingival Crevicular Fluid , Periodontitis , Calgranulin A , Cross-Sectional Studies , Humans , Periodontitis/diagnosis , Saliva
13.
Front Psychol ; 12: 691974, 2021.
Article in English | MEDLINE | ID: mdl-34135839

ABSTRACT

This study aimed to meta-analyze the relationship between self-management and exercise self-confidence, satisfaction, and commitment in both modern and traditional martial arts among Korean practitioners. We examined the level of sports participation and different martial arts sports as potential moderating variables. In total, 22 studies yielded 299 individual effect sizes and were included in the final meta-analytic pool. The analyses revealed a moderate effect of self-management on exercise satisfaction and self-confidence; and a large effect self-management on exercise commitment. Especially, the effect of the training dimension of self-management was large on exercise commitment and satisfaction, while that of the mental dimension was large on exercise self-confidence. The effects of self-management on exercise satisfaction, commitment, and self-confidence were large in judo, Ssireum, and wrestling, respectively. Finally, the use of self-management was relatively more effective for non-elite participants than for elite practitioners. Our results highlight the effectiveness of self-management to enhance Korean martial arts practitioners' exercise self-confidence, commitment, and satisfaction, findings that may potentially be extended internationally and to other types of sports; further, they showcase the importance of the promotion of interventions and educational programs on how to incorporate/employ self-management in athletes' sports training.

14.
BMC Geriatr ; 21(1): 245, 2021 04 14.
Article in English | MEDLINE | ID: mdl-33853530

ABSTRACT

BACKGROUND: Salivary function has been suggested to be associated with cognitive impairment. However, the effect of salivary flow rate (SFR) on cognitive impairment remains unclear. This study aimed to investigate whether SFR is associated with cognitive impairment among Korean elders. METHODS: This cross-sectional study included 649 elders aged 65 and older in the Korean community-dwelling population. Cognitive impairment was assessed using the Mini-Mental Status Examination. Unstimulated SFR was measured and dichotomized. Denture status, age, sex, education level, smoking, drinking, diabetes, hypertension, and obesity were considered confounders. Multivariable logistic regression analysis was applied to assess the adjusted association. Stratified analysis by sex and denture status was performed to clarify the effect modification. RESULTS: Participants without cognitive impairment showed a higher SFR level than those with cognitive impairment (0.81 mL/min for non-cognitive impairment versus 0.52 mL/min for cognitive impairment, p < 0.001). After controlling for confounders, participants with low SFR (< 0.3 mL/min) were more likely to have cognitive impairment by 1.5 times than participants with normal SFR (odds ratio [OR] = 1.5, confidence interval [CI] = 1.05-2.10). The association of low SFR with cognitive impairment was higher in women and dentate participants: about 10% higher in women (OR = 1.63, CI = 1.07-2.50) and about 22% higher in dentate participants (OR = 1.82, CI = 1.41-2.90). CONCLUSIONS: Salivary flow rate is independently associated with cognitive impairment among Korean elders. The association was modified in females and dentate elders. Physicians and dentists should consider low SFR and cognitive impairment as a risk factor between them in clinics.


Subject(s)
Cognitive Dysfunction , Salivation , Aged , Cognitive Dysfunction/diagnosis , Cognitive Dysfunction/epidemiology , Cross-Sectional Studies , Female , Humans , Independent Living , Male , Republic of Korea/epidemiology , Risk Factors
15.
Front Psychol ; 12: 658599, 2021.
Article in English | MEDLINE | ID: mdl-33868132

ABSTRACT

The present study examined the attitudes of Filipino middle school students toward physical education (PE) and the associations between PE attitude and various personal and external correlates of PE. In total, 659 middle school students, aged between 12 and 19 years (M = 14.55; SD = 1.14), participated in the study. The Physical Education Attitude Scale (PEAS) was used to measure affective, cognitive, and motivational/behavioral attitudes of adolescent students toward PE. Results showed that middle school students had moderate general attitudes toward PE. Female students had more favorable attitudes toward PE when their teacher was male than female. When the teacher was female, male students were more satisfied with the PE curriculum than female students. When the teacher was male, female students were more comfortable with the PE curriculum than male students. Finally, students' PE attitude did not decrease as they got older, regardless of student sex. The findings provide a different perspective for the field and underscore the importance of not only the PE curriculum but also the student-teacher relationship. To prevent the decline in students' positive attitude and encourage positive behaviors toward PE and activities, teachers should be very considerate about their interactions with students of the same sex; school administrators (e.g., principal and PE department head), meanwhile, should focus at providing PE teachers with special training courses to enhance both their teaching and communication capabilities.

16.
J Korean Med Sci ; 36(15): e98, 2021 Apr 19.
Article in English | MEDLINE | ID: mdl-33876587

ABSTRACT

BACKGROUND: Not so many reports about the association between head and neck cancer (HNC) and oral health status related to periodontitis (OHS-P) has been published in different countries with different methods. So, there is a need for an extensive meta-analysis with the total articles published until 2020. Hence, this study aimed to estimate the association between HNC and OHS-P through a meta-analysis. METHODS: Based on Preferred Reporting Items for Systematic Reviews and Meta Analyses guidelines, 22 studies were selected through PubMed and Cochrane Library databases. Meta-analysis using them was performed to evaluate the association. The risk of bias assessment using the Newcastle-Ottawa Scale (NOS) was applied to evaluate the quality of non-randomized studies. Publication bias was evaluated by funnel plot and Egger's regression test. RESULTS: Since heterogeneity was significant (I² = 88%, P < 0.001), we adopted the random effect model for 22 studies. Those with bad OHS-P, compared to those with good OHS-P, were more likely to have the risk of HNC by 2.4 times (odds ratio [OR], 2.42; 95% confidence interval [CI], 1.88-3.13) for random effect model. The association included publication bias (Egger's regression, P value < 0.001). The association among five studies (I² = 39%, P = 0.16) using alveolar bone loss (ABL) or clinical attachment level (CAL) for assessing periodontitis increased to OR of 3.85 (CI, 3.04-4.88) in the fixed effect model without publication bias (Egger's regression, P = 0.66). Moreover, the association was higher in 10 fair or good NOS studies (OR, 3.08) and in 7 Asian studies (OR, 2.68), which were from the fixed model without publication bias. CONCLUSION: Our meta-analysis showed that bad OHS-P was associated with the risk of HNC. The association was stronger in studies using ABL or CAL for assessing periodontitis.


Subject(s)
Alcohol Drinking , Head and Neck Neoplasms/diagnosis , Oral Health , Periodontitis/pathology , Smoking , Databases, Factual , Heart Disease Risk Factors , Humans , Odds Ratio
17.
PLoS One ; 16(3): e0247947, 2021.
Article in English | MEDLINE | ID: mdl-33661974

ABSTRACT

This study aimed to evaluate the association of periodontitis with the organoleptic score (OLS)-defined oral malodor after validating OLS with odoriferous sulfur compounds in mouth air among Korean adults. A total of 330 adults aged 47-86 years were recruited from the Yangpyeong health cohort, South Korea, in 2015. Oral malodor was assessed using a 6-point OLS by a trained dentist and validated with the concentrations of hydrogen sulfide (HS) and methyl mercaptan (MM) using a gas chromatographer. Periodontitis was measured by assessing the radiographic alveolar bone loss on digital orthopantomography. Statistical analyses including descriptive statistics, partial correlation, ANOVA, and multivariable logistic regression with putative confounders were applied. OLS was significantly correlated with the concentrations of HS and MM (partial r = 0.401 and 0.392, respectively; both p<0.001) after controlling for confounders. Individuals with periodontitis had 1.8 times the risk of OLS-defined oral malodor in multivariable models (adjusted odds ratio = 1.77 in the model with the number of teeth and 1.82 in the model with denture wearing; p = 0.047 and 0.035, respectively). Periodontitis was associated with OLS-defined oral malodor among Korean adults independent of known confounders. Periodontal conditions should be considered for clinical practice and research of oral malodor.


Subject(s)
Halitosis/etiology , Periodontitis/complications , Aged , Aged, 80 and over , Cross-Sectional Studies , Female , Halitosis/diagnosis , Humans , Male , Middle Aged , Periodontitis/diagnosis , Republic of Korea/epidemiology , Sensation , Sulfur Compounds/analysis
18.
PLoS One ; 16(3): e0248167, 2021.
Article in English | MEDLINE | ID: mdl-33735248

ABSTRACT

Over 90% of oral cancers are oral squamous cell carcinoma (OSCC). Hitherto, early detection marker for OSCC has not been available. Hence, this study aimed to evaluate the diagnostic and prognostic ability of salivary matrix-metalloproteinase-9 (MMP-9) and 8-hydroxydeoxyguanosine (8-OHdG) for OSCC. Total of 318 participants with 106 cases and 212 controls were included: OSCC cases were from Seoul National University Dental Hospital and age, sex, and smoking matched controls were from Yangpyeong cohort. Unstimulated saliva was collected to determine MMP-9 and 8-OHdG using sensitive enzyme-linked immunosorbent assay. Multivariable linear regression and analysis of covariance (ANCOVA) were applied to evaluate the adjusted association of markers with OSCC. Wilcoxon sign rank sum test and Friedman test for median were applied to evaluate follow-up level of MMP-9 after surgery. Receiver operating characteristic curve was obtained for diagnostic ability. Salivary MMP-9 was associated with OSCC (ANCOVA and multivariable linear regression, p<0.05), while 8-OHdG was not. The diagnostic ability of MMP-9 was area under curve of 0.96 (100% specificity and 89.6% sensitivity, p<0.001). MMP-9 decreased dramatically after tumor surgery (p<0.05). Salivary MMP-9 could be a critical diagnostic and prognostic marker for OSCC.


Subject(s)
Matrix Metalloproteinase 9/analysis , Mouth Neoplasms/diagnosis , Saliva/chemistry , Squamous Cell Carcinoma of Head and Neck/diagnosis , Aged , Female , Humans , Male , Middle Aged , Mouth Neoplasms/metabolism , Mouth Neoplasms/surgery , Prognosis , Squamous Cell Carcinoma of Head and Neck/metabolism , Squamous Cell Carcinoma of Head and Neck/surgery , Treatment Outcome
19.
J Clin Periodontol ; 47(11): 1354-1361, 2020 11.
Article in English | MEDLINE | ID: mdl-32841379

ABSTRACT

AIM: This cross-sectional study aimed to examine the diagnostic ability of salivary matrix metalloproteinase (MMP)-9 lateral flow test (LFT) point-of-care (POC) kit and develop an algorithm for diagnosis of periodontitis. MATERIALS AND METHODS: Through Seoul National Dental Hospital, 137 participants (46 LFT negatives, 91 LFT positives) were recruited. For salivary diagnostics, 150 µl of the unstimulated saliva was applied to LFT-POC kit. To make a diagnosis of periodontitis, stage II-IV in modified new international classification system was used. Covariates encompassing age, sex, smoking and obesity were evaluated through face-to-face interview. Enzyme-linked immunosorbent assay was used for quantification of salivary MMP-9. To develop a diagnostic algorithm, multivariable logistic regression analysis was used. Receiver operating characteristic curve was applied for evaluating diagnostic ability. RESULTS: Diagnostic ability of salivary MMP-9 LFT-POC test was 0.82 (sensitivity of 0.92, specificity of 0.72) in total participants. Diagnostic algorithm using POC test resulted in a response equation, that is algorithm score = -3.675 + 2.877*LFT + 0.034*age + 0.121*sex + 0.372*smoking + 0.192*obesity. Diagnostic ability of the algorithm was 0.88 (sensitivity of 0.92, specificity of 0.85) with cut-off score of 0.589. CONCLUSIONS: Salivary MMP-9 LFT-POC kit showed appropriate diagnostic ability for periodontitis and would be an efficient tool for screening of periodontitis.


Subject(s)
Matrix Metalloproteinase 9 , Periodontitis , Biomarkers , Cross-Sectional Studies , Humans , Infant , Matrix Metalloproteinase 8 , Periodontitis/diagnosis , Point-of-Care Testing , Saliva
20.
J Clin Periodontol ; 47(10): 1191-1200, 2020 10.
Article in English | MEDLINE | ID: mdl-32744384

ABSTRACT

OBJECTIVES: Salivary diagnostic using matrix metalloproteinase (MMP) and S100 for periodontitis is a promising issue. However, its prognostic effect is still unclear. This study aimed to evaluate the prognostic ability of salivary MMP-9 and S100A8 for periodontitis through non-surgical periodontitis treatment clinical trial. MATERIALS AND METHODS: Total 149 participants, 99 periodontitis and 50 healthy, were recruited. Among 99 non-surgical periodontitis treatment participants, 74 participants were revisited after three months. Periodontitis was classified as stage II-IV of new classification of periodontitis proposed at 2018. Enzyme-linked immunosorbent assay kit was used to quantify salivary MMP-9 and S100A8. Receiver operating characteristic curve was applied for diagnostic ability. Paired t test was applied for prognostic ability evaluating changes in salivary markers between pre- and post-treatment. RESULTS: Salivary MMP-9 and S100A8 were associated with periodontitis (p < .05). The screening ability of algorithm using salivary MMP-9 and S100A8 for periodontitis was 0.86 (p < .05). After treatment, reduction rate of salivary S100A8 and MMP-9 was 83.7% and 23.5%, respectively, (p < .05): only salivary S100A8 was superior compared to clinical parameters. CONCLUSION: Algorithm using salivary MMP-9 and S100A8 showed high diagnostic power for periodontitis. Both salivary S100A8 and MMP-9 showed prognostic ability for periodontitis, but S100A8 was better.


Subject(s)
Matrix Metalloproteinase 9 , Periodontitis , Biomarkers , Humans , Matrix Metalloproteinase 8 , Periodontitis/diagnosis , Prognosis , Saliva
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