ABSTRACT
BACKGROUND: Dry eye disease is an aging-related ophthalmic disease that not only affects the daily activities but also causes deterioration in the quality of life. This study aimed to evaluate the factors associated with dry eye symptoms in elderly Koreans. METHODS: We investigated 4,185 subjects (men=1,787 and women=2,398) aged ≥65 years from the fifth Korea National Health and Nutrition Examination Survey 2010-2012. Data were analyzed using multiple logistic regressions to identify the relationships between dry eye symptoms and other factors. RESULTS: The prevalence of dry eye symptoms was 17.9%. After adjustment for confounding factors, dry eye symptoms were significantly associated with female sex (adjusted odds ratio [aOR], 1.806; 95% confidence interval [CI], 1.410-2.313), a history of cataract (aOR, 1.683; 95% CI, 1.255-2.255), suicidal ideation (aOR, 1.414; 95% CI, 1.070-1.870), hypercholesterolemia (aOR, 1.289; 95% CI, 1.025-1.621), age ≥80 years (aOR, 0.538; 95% CI, 0.337-0.859), and sleep duration ≥9 h/d (aOR, 0.524; 95% CI, 0.330-0.834). CONCLUSION: Among elderly Koreans, female sex, a history of cataract, suicidal ideation, and hypercholesterolemia may be the risk factors for dry eye symptoms, whereas sleep duration ≥9 h/d can be a protective factor against dry eye symptoms.
ABSTRACT
BACKGROUND: The association between sleep duration and body composition measures in Korean adults remains unclear. METHODS: This cross-sectional study included 3,532 subjects aged ≥40 years (1,542 men and 1,990 women) who participated in the 2010 Korea National Health and Nutrition Examination Survey V-1. Self-reported sleep duration and anthropometric data were collected. Appendicular skeletal muscle mass (ASM) was quantified via dual-energy X-ray absorptiometry. Obesity was defined according to the body mass index and waist circumference. Sarcopenia was defined as the muscle mass percentage (ASM/weight) below the lowest quintile computed for the study population. Multivariate logistic regressions with or without adjustment for sociodemographic and lifestyle factors were used to evaluate the association of sleep duration with obesity and sarcopenia for participants who slept ≤5, 6-8, and ≥9 h/d. The results were expressed as odds ratios (ORs) with 95% confidence intervals (95% CIs). RESULTS: In women, the association between sleep duration and sarcopenia was stronger for individuals who slept ≥9 h/d than for those who slept 6-8 h/d (unadjusted OR, 1.99; 95% CI, 1.19-3.34; adjusted OR, 1.77; 95% CI, 1.06- 2.96). CONCLUSION: Longer sleep duration is associated with a significantly higher incidence of sarcopenia in Korean women aged ≥40 years.
