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Association of interleukin-10 gene promoter polymorphism in children with atopic dermatitis.

Sohn, Myung Hyun; Song, Jae Seok; Kim, Kyung-Won; Kim, Eun-Soo; Kim, Kyu-Earn; Lee, Jae Myun.

J Pediatr ; 150(1): 106-8, 2007 Jan.

Article in English | MEDLINE | ID: mdl-17188628

ABSTRACT

The present study evaluated the possible role of interleukin (IL)-10 promoter polymorphisms in children with atopic dermatitis (AD). IL-10 promoter polymorphisms are associated with the phenotype of AD in children.

Subject(s)

DNA/genetics , Dermatitis, Atopic/blood , Interleukin-10/genetics , Polymorphism, Genetic , Promoter Regions, Genetic/genetics , Alleles , Antibodies, Anti-Idiotypic , Biomarkers/blood , Child , Dermatitis, Atopic/genetics , Dermatitis, Atopic/immunology , Eosinophils/pathology , Female , Gene Frequency , Genetic Predisposition to Disease , Genotype , Humans , Immunoglobulin E/immunology , Interleukin-10/blood , Leukocyte Count , Male , Polymerase Chain Reaction

ABSTRACT

Subject(s)

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