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Neurol Res ; 37(3): 189-96, 2015 Mar.
Article in English | MEDLINE | ID: mdl-25213599

ABSTRACT

OBJECTIVES: Coil embolization of wide-necked and fusiform aneurysms is challenging and is frequently associated with recanalization despite assistance of any additional device. The purpose of this study was to evaluate the feasibility and mid-term outcomes of complex aneurysms after multiple overlapping stent-assisted coiling (OSAC). METHODS: We retrospectively evaluated 26 wide-necked and fusiform atherosclerotic or dissecting aneurysms that were treated with multiple OSAC. Eight aneurysms (30·8%) presented with subarachnoid hemorrhage and one (3·9%) with intracranial hemorrhage. RESULTS: Complete embolization was achieved in 15 of the 26 aneurysms (57·7%), while remnant neck was identified in nine (34·6%) and remnant aneurysm was noted in two (7·7%). Immediate procedure-related complications were observed in five patients (19·2%) including two with asymptomatic in-stent thrombosis, one with transient right-sided weakness, one with decreased mentality, and one with aphasia and quadriplegia. A procedure-related permanent neurologic deficit (modified Rankin scale scores of 1 and 5) was noted in two patients (7·7%). Angiographic follow-up (mean duration 23·9 months) after OSAC was carried out in 18 patients (69·2%): 11 (61·1%) were stable, 3 (16·7%) improved, 3 (16·7%) had minor compaction, and 1 had major recanalization (5·5%). One recurred aneurysm after OSAC and two recanalized aneurysms after single stenting were re-treated using additional stent-assisted coiling, and there was no recanalization in these three aneurysms during the 25·7 months after re-treatment. CONCLUSIONS: Multiple OSAC is feasible and effective for complex aneurysms and recurrent aneurysms after stent-assisted coiling.


Subject(s)
Aortic Dissection/therapy , Embolization, Therapeutic/instrumentation , Embolization, Therapeutic/methods , Intracranial Arteriosclerosis/therapy , Stents , Adult , Aged , Aortic Dissection/pathology , Angiography , Embolization, Therapeutic/adverse effects , Feasibility Studies , Female , Follow-Up Studies , Humans , Intracranial Aneurysm/pathology , Intracranial Aneurysm/therapy , Intracranial Arteriosclerosis/pathology , Male , Middle Aged , Retreatment , Retrospective Studies , Stents/adverse effects , Subarachnoid Hemorrhage/pathology , Subarachnoid Hemorrhage/therapy
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