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Chem Commun (Camb)
; 59(61): 9388-9391, 2023 Jul 27.
Article
in English
| MEDLINE
| ID: mdl-37435665
ABSTRACT
Nanopore sequencing maps biochemical processes on DNA by detecting negative peaks in the sequence alignment profile. Protein-bound DNA and single-strand broken DNA cannot pass through nanopores, resulting in unaligned regions in the genome MAP. This novel approach provides a clear representation of genomic biochemical events.