ABSTRACT
Haemorrhagic pancarditis has been studied microscopically and ultrastructurally. Haemorrhages, oedema, mononuclear cell infiltration, degeneration, fragmentation, atrophy and lysis of myofibres, and extravascular localisation of the parasite were observed.
Subject(s)
Cattle Diseases/pathology , Heart Diseases/veterinary , Hemorrhage/veterinary , Myocardium/pathology , Trypanosomiasis, Bovine/complications , Animals , Cattle , Cattle Diseases/etiology , Endocarditis/etiology , Endocarditis/pathology , Endocarditis/veterinary , Heart Diseases/etiology , Heart Diseases/pathology , Hemorrhage/etiology , Hemorrhage/pathology , Male , Microscopy, Electron , Myocarditis/etiology , Myocarditis/pathology , Myocarditis/veterinary , Myocardium/ultrastructure , Pericarditis/etiology , Pericarditis/pathology , Pericarditis/veterinaryABSTRACT
Skin lesions of bovine East Coast fever were examined by light and electron microscopy at 120 hours after attachment of Rhipicephalus appendiculatus ticks infected with Theileria parva. Lesions included epidermal ulcer, hemorrhage, edema, necrosis, and inflammatory cell infiltration by mostly polymorphonuclear and mononuclear (lymphoid) cells. The trophozoite state of T parva was observed in a parasitophorous vacuole and feeding on neutrophil granules. Schizonts, some in budding process, and merozoites were extracellular and among many mononuclear phagocytes (lymphoid cells). Some merozoites were in mononuclear phagocytes and a granulocyte. Some of the cells had already transformed into lymphoblasts with pseudopodia.
Subject(s)
Skin/ultrastructure , Theileriasis/pathology , Animals , Apicomplexa/ultrastructure , Cattle , Female , Leukocytes/parasitology , Leukocytes/ultrastructure , Male , Phagocytes/parasitology , Phagocytes/ultrastructure , Skin/parasitology , Theileriasis/parasitologyABSTRACT
The sequence of ultrastructural changes of bovine platelets during the fatal course of East Coast fever was swelling; formation of vacuoles, pseudopodia, and indentations; then thrombocytorrhexis and degranulation; and finally, thrombocytolysis. These changes led to thrombocytopenia and release of serotonin, resulting in petechiations and pulmonary edema.
