An investigation of associations between experience of childhood trauma and political violence and theory of mind impairments in schizophrenia.

There has been little examination of the association between trauma and cognitive deficits seen in individuals diagnosed with schizophrenia. Theory of Mind (ToM) impairments are a significant feature of schizophrenia but it remains unclear as to why these deficits are so prevalent in this population. This study aimed to explore associations between ToM deficits and specific forms of childhood adversities in a schizophrenia population. The study sample comprised of 66 adults with a confirmed diagnosis of schizophrenia, attending mental health services in Northern Ireland. Assessments were completed to ascertain if individuals had prior experience of sexual or physical abuse, emotional neglect or experience of the political violence of Northern Ireland's "Troubles", and the Gardner Hinting Test was applied to assess ToM ability. Backwards stepwise regression analyses demonstrated that emotional neglect, specifically during early childhood (0-6 years) predicted ToM impairments in this group. Conflict-related trauma was also associated with ToM but was not an independent significant predictor of ToM deficits. This is the first study to examine links between specific forms of childhood adversity and ToM impairments in individuals diagnosed with schizophrenia. Potential underpinning psychological mechanisms are considered and implications for clinical practice are discussed.

What is the prevalence of autism spectrum disorder and ASD traits in psychosis? A systematic review.

There is increasing evidence to suggest both a symptomatic overlap and a clinically significant degree of co-occurrence between Autism Spectrum Disorders (ASD) and psychotic disorders such as schizophrenia but the nature of such relationships remain unclear. We reviewed the literature reporting prevalence rates of Autistic-like Traits (ALTs) and ASD in populations with a diagnosis of schizophrenia or other psychotic disorder. A search of three large databases was conducted and from this seven studies met the criteria for inclusion. The point prevalence rates for ALTs ranged from 9.6% to 61%, whilst the prevalence rates for diagnosed ASD ranged from <1% to 52% across outpatient and inpatient populations. This suggests that prevalence rates of ALTs and ASD in psychosis populations are much higher than in the general population. This has important implications regarding future research, and clinical implications in terms of ensuring that patients receive the most appropriate diagnosis and treatment.