ABSTRACT
High risk groups of infants with regard to sepsis are described. The first high risk group includes newborn babies, infants of the first 3 months of age, premature babies, the second babies with congenital defects of the immune system (classified and unclassified defects), the third babies with acquired immune deficiency conditions due predominantly to the pathology of therapy. Septicemia remains the main clinico-anatomical form of sepsis in infants. The morphological criteria of this form of sepsis are described. In the lack of decrease of sepsis incidence in infants pathology of a therapy plays a great role, but it should be remembered that sepsis nowadays is observed in babies who previously had died within a short period of time after birth or after the onset of the disease.
Subject(s)
Bacterial Infections/pathology , Immunologic Deficiency Syndromes/congenital , Mycoses/pathology , Sepsis/pathology , Catheterization , Disseminated Intravascular Coagulation/etiology , Erythroblastosis, Fetal/complications , Female , Humans , Infant , Infant, Newborn , Infant, Premature, Diseases/pathology , Pregnancy , Risk , Subclavian Vein , Umbilical VeinsSubject(s)
Arteritis/pathology , Infant, Newborn, Diseases/pathology , Staphylococcal Infections/pathology , Streptococcal Infections/pathology , Thrombosis/pathology , Umbilical Arteries/pathology , Umbilical Veins/pathology , Female , Humans , Infant , Infant, Newborn , Male , Necrosis , Sepsis/pathology , Staphylococcus aureusABSTRACT
Four observations of Candida sepsis in young infants are described, analysing the pathways for fungus penetration, discussing the organ pathology and features of morphological reactions in infants. In one case primary immunodeficiency of the cellular-humoral type was established.
