ABSTRACT
The authors studied influence of vibration, noise, physical overexertion and microclimate on carbohydrates metabolism and insulin resistance in metal mining industry workers. Findings are that vibration disease appeared to have maximal effect on insulin resistance test results and insulin level. The authors suggested biomarkers for early diagnosis of insulin resistance disorders in metal mining industry workers.
Subject(s)
Carbohydrate Metabolism/physiology , Metallurgy , Microclimate , Mining , Noise, Occupational/adverse effects , Occupational Diseases/etiology , Physical Exertion , Vibration/adverse effects , Humans , Occupational Diseases/epidemiology , Occupational Diseases/metabolism , RussiaABSTRACT
The article deals with new scientific data on influence of industrial vibration on prevalence of androgen deficiency in vibration disease pateints, correlation between androgen deficiency level and general somatic diseases in vibration disease patients, criteria of early diagnosis of the combined pathology.
Subject(s)
Androgens/deficiency , Occupational Diseases/physiopathology , Vibration/adverse effects , Adult , Humans , Male , Middle Aged , Occupational Diseases/etiologyABSTRACT
The authors studied influence of vibration on serum neurotropic protein S100B level in miners. Vibration appeared to cause significant effect on increase of this protein level. With that, there is a moderate correlation between the protein level and intensity of the vibration effect.
Subject(s)
Autonomic Nervous System Diseases , Coal Mining , Occupational Diseases , S100 Calcium Binding Protein beta Subunit/blood , Vibration/adverse effects , Adult , Autonomic Nervous System Diseases/blood , Autonomic Nervous System Diseases/epidemiology , Autonomic Nervous System Diseases/etiology , Autonomic Nervous System Diseases/physiopathology , Humans , Lipids/blood , Male , Middle Aged , Occupational Diseases/blood , Occupational Diseases/epidemiology , Occupational Diseases/etiology , Occupational Diseases/physiopathology , Occupational Exposure/adverse effects , Russia/epidemiology , Severity of Illness Index , Statistics as TopicABSTRACT
The article presents study results that demonstrate chronic fatigue syndrome in patients with vibration disease. Clinical manifestations of chronic fatigue syndrome are characterized by changes in the emotional-volitional and cognitive areas. Application of nootropic drug cortexin increases the efficiency of rehabilitation in patients with vibration disease with chronic fatigue syndrome.
Subject(s)
Fatigue Syndrome, Chronic/etiology , Hand-Arm Vibration Syndrome/complications , Occupational Exposure/adverse effects , Vibration/adverse effects , Adult , Cognition/physiology , Cytokines/blood , Emotions , Fatigue Syndrome, Chronic/epidemiology , Fatigue Syndrome, Chronic/immunology , Fatigue Syndrome, Chronic/psychology , Hand-Arm Vibration Syndrome/epidemiology , Hand-Arm Vibration Syndrome/immunology , Hand-Arm Vibration Syndrome/psychology , Humans , Male , Middle Aged , Neuropsychological Tests , Occupational Exposure/analysis , Russia , Severity of Illness IndexABSTRACT
The question to include locomotory disorders into set of symptoms of vibration disease due to local vibration is discussed over years. Studies of clinical symptoms of vibration disease in machinery construction workers demonstrated that bone and joint changes risk depends on intensity of vibration factor and length of exposure to local vibration, as well as on work hardiness. The authors specified X-ray criteria of bone and joint disorders and laboratory markers of bone tissue injury under exposure to local vibration.
Subject(s)
Hand-Arm Vibration Syndrome/pathology , Hand-Arm Vibration Syndrome/physiopathology , Joints/pathology , Joints/physiopathology , Upper Extremity/pathology , Upper Extremity/physiopathology , Female , HumansABSTRACT
The paper presents the results of transcranial electrical stimulation (TES) in treating patients with vibration disease and occupational lumbosacral radiculopathy. It is shown that the inclusion of TES in the program of rehabilitation therapy gives a more pronounced clinical effect, helps to reduce pain, has psychological correcting antidepressant action significantly, improves the quality of life of patients. The study results enable to recommend TES in the complex medical and rehabilitative measures as an effective and pathogenetically substantiated method of treatment of patients with occupational diseases of the nervous system.
Subject(s)
Occupational Diseases/therapy , Polyneuropathies/therapy , Radiculopathy/therapy , Transcutaneous Electric Nerve Stimulation/methods , Vibration/adverse effects , Adult , Humans , Lumbosacral Region , Middle Aged , Neuropsychological Tests , Occupational Diseases/etiology , Occupational Diseases/psychology , Polyneuropathies/etiology , Polyneuropathies/psychology , Quality of Life , Radiculopathy/etiology , Radiculopathy/psychology , Surveys and Questionnaires , Transcutaneous Electric Nerve Stimulation/instrumentation , Treatment OutcomeABSTRACT
The article presents study results that demonstrate biochemical and neurohumoral disorders in machinery construction workers. The authors defined characteristics of changed functional state of adrenocorticotropic and luteotropic regulation, that is presented in central and peripheral endocrine system divisions.
Subject(s)
Hormones/metabolism , Metallurgy , Occupational Diseases/metabolism , Adrenocorticotropic Hormone/blood , Adrenocorticotropic Hormone/metabolism , Adult , Antioxidants/metabolism , Blood Glucose/analysis , Follicle Stimulating Hormone/blood , Follicle Stimulating Hormone/metabolism , Glucose Tolerance Test , Growth Hormone/blood , Growth Hormone/metabolism , Hormones/blood , Humans , Lipid Metabolism , Lipid Peroxidation , Luteinizing Hormone/blood , Luteinizing Hormone/metabolism , Middle Aged , Noise, Occupational/adverse effects , Occupational Diseases/blood , Vibration/adverse effectsABSTRACT
Neuro-psychologic studies demonstrated that alexithymia manifestations are more frequent in vibration disease patients than in the reference group. With the disease progress alexithymia increases. Alexithymic traits are combined with neurologic disorders, increased anxiety, inclination to depressive response to stress situation. Using nootropics increases efficiency of rehabilitation in vibration disease patients having alexithymia symptoms.
Subject(s)
Affective Symptoms/etiology , Hand-Arm Vibration Syndrome/complications , Vibration/adverse effects , Adult , Affective Symptoms/prevention & control , Affective Symptoms/psychology , Disease Progression , Hand-Arm Vibration Syndrome/drug therapy , Hand-Arm Vibration Syndrome/psychology , Humans , Middle Aged , Nootropic Agents/therapeutic use , Psychometrics/methodsABSTRACT
Vibration disease in miners is characterized by various neurologic signs: vegetative sensory polyneuropathy, cerebral and vertebrogenic symptoms. Antioxidant medications help to increase efficiency of therapeutic and preventive measures in vibration disease.
Subject(s)
Electroencephalography/methods , Mining , Occupational Diseases/diagnosis , Thermography/methods , Vibration/adverse effects , Body Temperature/physiology , Diagnosis, Differential , Disease Progression , Female , Humans , Male , Middle Aged , Occupational Diseases/etiology , Occupational Diseases/physiopathology , Prognosis , Time FactorsABSTRACT
The article covers complex clinical and laboratory study in 140 workers with mining occupations in relation to climate and geographic location of the industrial enterprises. The examinees received ultrasound densitometry, X ray study of bone tissue, bone resorption and osteogenesis markers examination. All observations reliably demonstrated manifestations of osteopenic syndrome in workers engaged into the studied industrial branches.
Subject(s)
Climate , Mining , Occupational Diseases/diagnosis , Occupational Exposure/adverse effects , Osteoporosis/diagnosis , Vibration/adverse effects , Absorptiometry, Photon/methods , Humans , Male , Middle Aged , Occupational Diseases/epidemiology , Occupational Diseases/etiology , Osteoporosis/epidemiology , Osteoporosis/etiology , Prevalence , Russia/epidemiologyABSTRACT
The study covered prevalence of metabolic syndrome and its risk factors among mining and machinery industry workers. Reliably higher incidence of metabolic syndrome was revealed in workers exposed to vibration, when compared with the reference group. The authors calculated relative risk of metabolic syndrome development after exposure to the factor studied.
Subject(s)
Metabolic Syndrome/epidemiology , Mining , Occupational Diseases/epidemiology , Occupational Exposure/adverse effects , Vibration/adverse effects , Adult , Humans , Incidence , Male , Metabolic Syndrome/etiology , Middle Aged , Occupational Diseases/etiology , Risk Factors , Russia/epidemiologyABSTRACT
Having analyzed literature data and results of their own research, the authors describe early alterations on the cellular and molecular levels of the organism in exposure to local and general vibration. Those include changes in oxidative metabolism, immune shifts, lesions of cell membranes, deterioration of blood rheology, lesions of muscular and connecting tissues, disturbances of mineral exchange. The paper suggests a complex of laboratory tests for early detection of prepathological conditions of the organism in exposure to vibration. It includes measurement of certain parameters, such as the serum levels of vitamin E, malonic dialdehyde, immunoglobulins IgA, IgM, IgG, circulating immune complexes as well as assessment of antioxidative activity, peroxide erythrocyte hemolysis, spontaneous and ADF-induced thrombocyte aggregation, measurement of erythrocyte diameter and volume, creatinine and oxiproline urine concentration, myoglobine blood level and copper serum level. The above parameters are of sufficiently high diagnostic sensitivity and reflect the main aspects of vibratory pathology pathogenesis.
Subject(s)
Occupational Diseases/diagnosis , Occupational Diseases/etiology , Vibration/adverse effects , Antigen-Antibody Complex/analysis , Antigen-Antibody Complex/blood , Copper/blood , Creatinine/urine , Hemorheology , Humans , Lipid Peroxidation , Occupational Diseases/blood , Occupational Diseases/immunology , Occupational Diseases/metabolism , Occupational Diseases/urine , Sensitivity and Specificity , Time Factors , Vitamin E/bloodABSTRACT
Miners of basic professions employed in contemporary metal mining industry are exposed to a range of industrial factors, such as vibration, noise, dustiness, and unfavorable microclimate. Long-term exposure to these factors is hazardous to their health, which is manifested by elevated general and occupational morbidity and a higher rate of biological aging. This is most typical of Far North miners, who are exposed to the combination of the industrial factors and extremal climate and geographic conditions. Research into the health status of miners engaged to underground works and open excavations in regions with contrasting climate and geographic conditions, allowed determination of main industrial risk factors (vibration and noise), leading occupational diseases and groups of high risk of their development (according to the occupation and the length of service). The study found high risk of cardivascular diseases as well as pathology of the musculoskeletal system, which was highest in miners in Norilsk region.
Subject(s)
Cardiovascular Diseases/etiology , Mining , Musculoskeletal Diseases/etiology , Noise, Occupational/adverse effects , Occupational Diseases/etiology , Vibration/adverse effects , Adult , Cold Climate , Humans , Male , Metals , Middle Aged , Risk Factors , Siberia , Time FactorsSubject(s)
Occupational Diseases/metabolism , Occupational Medicine/methods , Oxidative Stress , Air Pollutants, Occupational/adverse effects , Antioxidants/therapeutic use , Dust , Free Radicals/metabolism , Humans , Lipid Peroxides/metabolism , Occupational Diseases/etiology , Occupational Diseases/prevention & control , Pneumoconiosis/etiology , Pneumoconiosis/metabolism , Pneumoconiosis/prevention & control , Vibration/adverse effectsSubject(s)
Cervical Vertebrae , Intervertebral Disc Displacement/diagnosis , Meningeal Neoplasms/diagnosis , Meningioma/diagnosis , Spinal Cord Compression/diagnosis , Amyotrophic Lateral Sclerosis/diagnosis , Amyotrophic Lateral Sclerosis/etiology , Cervical Vertebrae/pathology , Chronic Disease , Diagnosis, Differential , Female , Humans , Intervertebral Disc Displacement/complications , Magnetic Resonance Imaging , Meningeal Neoplasms/complications , Meningeal Neoplasms/surgery , Meningioma/complications , Meningioma/surgery , Middle Aged , Spinal Cord Compression/etiology , Spinal Cord Compression/surgery , Spinal Cord Neoplasms/diagnosisABSTRACT
The authors report a case of low spine vascular insufficiency. The clinical neurological syndrome resulted from compression of the accessory radiculomedullary artery by a dystrophic disk in a female patient with lumbar osteochondrosis. NMR tomography registered specific changes in the intervertebral disks and dural space which is decisive for differential diagnosis with similar symptoms of other affections.
