Microsurgical Clipping of Distal Basilar Trunk Aneurysm during Adenosine-Induced Profound Hypotension.

A 46-year-old male presented with a history of sudden severe headache 1 week back, altered sensorium and right hemiparesis for 2 days. On examination, Glasgow Coma Scale (GCS) was E4V4M6 and the patient had right hemiparesis (power - 4/5). Computed tomography (CT) revealed diffuse subarachnoid hemorrhage (Fisher's Grade III). CT angiogram revealed distal basilar trunk aneurysm arising between the origin of the left posterior cerebral artery and superior cerebellar artery, ectatic dilatation of distal basilar trunk, and a left middle cerebral artery (MCA) bifurcation aneurysm. Basilar trunk aneurysm was approached through subtemporal route and aneurysm was clipped during adenosine-induced profound hypotension (AIPH) without application of temporary clip. Single bolus 6 mg of adenosine was given, and aneurysm was successfully clipped during AIPH (systolic <60 mmHg). There were no complications related to adenosine. Ectatic part of distal basilar trunk was wrapped with Teflon. The left MCA bifurcation aneurysm was clipped in the same session. At 3-month follow-up, the patient's sensorium was normal (GCS-E4V5M6) and the right hemiparesis improved (4+/5). Adenosine enhances the safety of clipping these aneurysms by providing transient cardiac arrest or profound hypotension. In developing countries, microsurgical clipping is a cost-effective treatment option for basilar artery aneurysms.

Speech and Swallowing Function Outcome Following Early Tracheostomy in Patients Who Underwent Neurosurgical Intervention.

BACKGROUND: Evaluation of late-onset speech and swallowing complications of tracheostomy on neurotrauma cases, as the most common intensive care unit procedure, needs to be evaluated. OBJECTIVES: A prospective study conducted in a tertiary care teaching hospital to find the late-onset speech and swallowing complications of tracheostomy in neurotrauma cases. MATERIALS AND METHODS: This prospective observational study was conducted in the intensive care unit on intubated patients needing elective tracheostomy at a tertiary care teaching institute in South India with a dedicated referral trauma center. A data collection tool was prepared to find age, gender, date of admission, tracheostomy, and discharge, contact address and number, initial and final diagnosis, initial Glasgow Coma Scale (GCS) on admission and subsequent GCS before and after tracheostomy, ventilator settings before and after the tracheostomy, procedure and intraoperative complications, type of cannula used, details of decannulation, and respiratory difficulties. RESULTS: In our study among 69 cases between 16 and 75 years' age range with mean 46.67 ± 16.65, majority were males (75.36%) and 60 were cranial cases (86.96%). Of the alive cases (21 [30.43%]) who underwent tracheostomy; 18 were performed in operation theater and 3 as bedside procedure. Major problems reported were: Speech problems (not able to phonate) (9), feeble voice (6), pain while speaking (6), and reduced loudness (6), frequent throat clearing while speaking (4), cough while speaking (3); breathlessness while speaking (1), gasping while speaking (1) and vocal tiredness (1); aspirations (2) and painful swallowing (1). CONCLUSIONS: Our study suggested that though, majority of neurotrauma patients require tracheostomy for long term ventilator support and associated speech and swallowing problems are expected.

Management Issues in a Case of Congenital Craniovertebral Junction Anomaly with Aberrant Retropharyngeal Midline Course of Bilateral Cervical Internal Carotid Arteries at C1-C2.

BACKGROUND: Aberrant medial retropharyngeal prevertebral course of the internal carotid arteries (ICAs) is extremely uncommon. In oropharyngeal surgeries, like transoral odontoidectomy (TOO), this unrecognized aberrant retropharyngeal course of ICAs can result in devastating complications secondary to inadvertent injury of ICAs. We describe this aberrant course of ICAs in a patient with a craniovertebral junction (CVJ) anomaly with a dysmorphic C1 lateral mass on one side and discuss in detail various management issues in this complex case. CASE DESCRIPTION: A 44-year-old patient presented with neck pain, paresthesia in all 4 limbs, and quadriparesis. Computed tomography (CT) of the CVJ revealed os odontoideum, basilar invagination, atlantoaxial dislocation (AAD), severe malalignment of the C1-C2 facets, and an unusually thin (dysmorphic) left C1 lateral mass. Computed tomographic angiography revealed an aberrant medial retropharyngeal course of the bilateral cervical ICAs with near midline location at the level of C1 and C2. Transoral odontoidectomy (TOO) was not considered safe in view of potential injury to medially located ICAs. Normal spinal alignment with reduction of BI and AAD was achieved by C1-C2 joint distraction with placement of a spacer only in the right C1-C2 joint space followed by occipitocervical fusion. The patient experienced complete recovery after surgery with improvement of power in all 4 limbs to 5/5. CONCLUSIONS: Identification of this rare aberrant prevertebral course of ICAs in a patient with a CVJ anomaly is critical because it precludes TOO as a treatment option. Correction of BI and AAD is possible even with a unilateral C1-C2 joint spacer when placement of a joint spacer on the other side is not technically feasible.

Clinical study to assess the outcome in surgically managed patients of spontaneous intracerebral hemorrhage.

INTRODUCTION: Spontaneous intracerebral hemorrhage (SICH) subtype of stroke is characterized by bleeding into brain parenchyma which is not accompanied by trauma. Emergency surgical evacuation of large size SICH increases the chances of survival but does not help in functional recovery of the patients. The present study was conducted to assess the outcome of surgical management in patients with SICH. MATERIALS AND METHODS: All patients who were diagnosed with SICH and underwent surgical evacuation of the hematoma included in the study. The outcome at 1 month was obtained through follow-up visits/telephonic interview when the former is not available. The primary outcome measure was in hospital mortality/condition at the time of discharge/neurological deficit/modified Rankin Scale (mRS) at 1 month follow-up. RESULTS: Out of 87 patients, 49 patients (63%) were male and 38 patients (37%) were females, male to female ratio was 1.2:0.8. Nearly 42% patient had systolic blood pressure with in normal range; however, in almost 50% of the cases, the systolic blood pressure at the time of admission was more than 140 mmHg. mRS was assessed for the patients at the time of admission, 39% patients had slight disability, 15% patients had moderate disability, 11% patients had moderately severe disability, and 33% patients had severe disability. Mortality was relatively higher in patients who had admission systolic blood pressure more than 140 mmHg (51% vs. 43%). mRS was assessed for the patients at the time of discharge after completion surgery and the severity of scale. CONCLUSIONS: Hypertension was found to be most common comorbid illness followed by smoking, alcohol intake, and diabetes mellitus. Hematoma was evacuated in 58% of the cases; it was supplement with decompressive craniectomy in 12% of the cases. Morality was relatively higher in patients who had admission systolic blood pressure more than 140 mmHg. Mortality was highest in <40 years age group in age group of 40-65 years, the mortality was 30.6%, and in >65 years age group, mortality was 15.4%; however, this was not statistically significant. Only 10% of patients can recover and live independently at 1 month, and only 20% of the survivors were independent at 6 months.