[Intubation of trachea and bronchi in pulmonary hemorrhages]. / Intubatsiia trakhei i bronkhov pri legochnykh krovotecheniiakh

The authors made an attempt to evaluate the efficiency of different means of protecting the healthy lung section against hemo-aspiration in TB surgical patients with pulmonary hemorrhages applied at the stages of surgery and narcosis administration. A total of 70 patients with different pulmonary TB variations were examined within the case study. On the basis of a conducted analysis, the author concluded that the preoperative hemorrhage arrest is the most rational tactic in the described cases. It delays the surgical intervention and cuts the number of postoperative hemo-aspiration complications.

[Clinical characteristics of patients emergently hospitalized with pulmonary hemorrhage]. / Klinicheskaia kharakteristika bol'nykh ékstrenno gospitalizirovannykh s legochnym krovotecheniem.

Analyzing the data on 1812 patients with respiratory diseases, mainly pulmonary tuberculosis, urgently admitted to a tuberculosis hospital for the pulmonary hemorrhage (PH) syndrome during 5.5 years showed that there was no seasonal prevalence in the development of a complication. There was a steady-state regularity of the prevalent admission of patients to hospital from 10 a.m. to 8 p.m. and no hemorrhage in 39% of them on admission. Evidence was provided for the low diagnostic value of hemoptysis in assessing the prediction of the developed PH syndrome. In PH syndrome, the hospital mortality decreased by 2.6 times (from 20.0 to 7.7%) due to a wider use of the artificial hypotension method, endoscopic bronchial blockade, to the development and introduction of new modes of intraoperative protection and sanitation of the tracheobronchial tree, to the prevention of asphyxia, hemo-aspiration pneumonia, and its pathogenetically resultant acute progression of tuberculosis.

[Goodpasture's syndrome as a cause of pulmonary hemorrhages]. / Sindrom Gudpaschera kak prichina legochnykh gemorragii.

Analyzing the case histories of 5 patients with Goodpasture's syndrome who have admitted to an emergency clinic for suspected tuberculosis leads to the conclusion that the onset of the disease appeared as intoxication and lung damage, and evolving general weakness, fever, cough. Hemopoiesis appeared just when overall clinical manifestations appeared, it varied from single sputum blood filaments to more frequent mows of pure red blood sputum for several weeks, but there was never an increasing hourly progressively and this failed to cause a rapid drop of hemoglobin. Anemia is attributable by pulmonary blood imbibition, intoxication, and suppressed hemopoiesis in renal failure rather than by external blood loss as hemoptysis.

[Clinico-anatomical significance of the presence of blood in the gastrointestinal tract of patients who died of pulmonary hemorrhage]. / Kliniko-anatomicheskoe znachenie nakhozhdeniia krovi v zheludochno-kishechnom trakte u bol'nykh, umershikh ot legochnogo krovotecheniia.

Examining the follow-up and autoptic data on 133 patients who died from pulmonary hemorrhage in the presents of respiratory diseases, including tuberculosis has revealed a previously undescribed a phenomenon of the presence of blood varying in its pattern and volume in the proximal and distal gastrointestinal tract. The clinical and anatomic assessment of the phenomenon detected and its value in the patho- and thanatogenesis of asphyxial pulmonary hemorrhages are given. It is concluded that asphyxial hemorrhages do not develop suddenly, but they result from pulmonary hemorrhages lasting 1-2 days or more, wherein the patients digest great volumes of blood. The digesting of blood rather than its coughing away is observed in patients with mental disorders, during a deep or abnormal sleep, and in the agonal period of asphyxia. The paper shows the significance of the revealed phenomenon as a constituent of total blood loss and a cause of undiagnosed pulmonary hemorrhage in 24% of dead individuals.

[The effect of an ozone-oxygen mixture on Mycobacterium tuberculosis and conditionally pathogenic microorganisms]. / Vozdeistvie ozono-kislorodnoi smesi na mikobakterii tuberkuleza i uslovno-patogennye mikroorganizmy.

The impact of a gaseous ozone-oxygen mixture (OOM) on Mycobacterium tuberculosis (MBT) and opportunistic microorganisms was studied. It was demonstrated that on 15- and 30-min exposure, OOM caused a significant decrease in the number of colonies of the grown microorganisms as compared with the control. The OOM mixture produced the highest effect of the MBT suspension, which is likely to be related to a greater surface of ozone contact with a cell than with a dense medium, and higher concentration of ozone and its highly active radicals that arise from a treatment process. After treatment with a gaseous mixture, 80-90% of the microbial cells lost their reproductive ability. The strains grown after OOM action retain drug sensitivity of the original strain. The results suggest that the use of a gaseous OOM mixture is promising in the treatment of tuberculosis to cleanse the destruction cavities and pleural empyemas, including those of nonspecific etiology.