[Vasomotor Endothelial Function in Healthy Individuals: Contact Types of Character].

We studied the vascular endothelial vasomotor function in healthy young individuals, depending on the type of character accentuation, levels of neuroticism, depression and anxiety. It is shown that the types of character accentuation effect on endothelial vasomotor function in healthy men and women. Personality characteristics of a person can be a significant risk factor for disease, the pathogenesis of which is the starting element of endothelial vasomotor dysfunction.

Effect of continuous irradiation with terahertz electromagnetic waves of the NO frequency range on behavioral reactions of male albino rats under stress conditions.

We studied the effect of terahertz waves (NO frequency range, 150.176-150.664 GHz) on stress-induced variations in behavioral reactions of male albino rats during hypokinetic stress. THz irradiation was followed by partial or complete normalization of behavioral reactions of male albino rats after hypokinetic stress. The most significant effect was observed after continuous irradiation for 30 min.

[Microcirculation in the injured spleen by different operations in children].

43 children were operated on spleen injury: 14 were splenectomized; 29 splenectomy were completed with partial spleen tissue autotransplantation into the omentum. Changes of homeostatic system, hemoreology and immune status were followed up within 1 year after the operation, Connections between the type of the operation performed and the listed above changes were followed.

[Changes in the immune status of patients operated for splenic lesions in the late postoperative period and their relation to the development of complications].

This analysis of changes in the immune status of patients operated for splenic lesions is based on the observations of 126 subjects. Fifty of them underwent autolientransplantation and 26 conservative surgery. The main parameters of humoral and cellular immunity were measured along with changes in the microflora. Splenectomy was shown to cause changes in the characteristics of both cellular and humoral immunity. Autolientransplantation caused a significant decrease in the serum level of total complement and its C3- and C-4 fractions while the amount of circulating immune complexes increased All other parameters of the immune status remained unaltered The best outcome of the treatment was documented after conservative surgery.

Effects of terahertz radiation at atmospheric oxygen frequency of 129 GHz on blood nitrite concentrations under conditions of different types of stress against the background of administration of nonselective inhibitor of constitutive NO-synthases.

We studied the effect of terahertz radiation at atmospheric oxygen frequency 129 GHz on blood nitrite concentration in different types of experimental stress against the background of administration of nonselective inhibitor of constitutive NO-synthases. Normalizing effects of radiation on blood nitrite dynamics in animals with acute stress was shown after 15-min exposure and in animals with chronic stress after 30-min exposure. No positive effect of terahertz radiation was observed on altered blood nitrite concentration in male rats after preliminary administration of nonselective constitutive NO-synthase isoform inhibitor L-NAME.

[Changes gas and electrolyte structure of blood under influence terahertz radiations on frequencies nitrogen oxide 150,176-150,664 GHz in the conditions of stress].

Influence terahertz radiations nitrogen oxide frequencies of 150,176 - 150,664 GHz on gas and electrolyte structure of blood of white rats being in condition of sharp stress. It is shown that at 15 minute mode of influence terahertz waves on frequencies nitrogen oxide observe partial restoration of studied indicators gas and electrolyte structure of blood at stress animals. At 30 minute mode of influence the specified waves observe complete recovery of the broken indicators gas and electrolyte blood structure.

[Evaluation of the course of an infectious process by erythrocyte membrane permeability].

The physical and chemical parameters of red blood cells were studied in patients with urinary tract infection. The permeability parameters were proposed to study erythrocyte membrane permeability. Complete recovery of the latter in patients with somatic diseases due to antibacterial therapy was found to suggest that the preservation of erythrocyte dysfunction.

Correction of microcirculatory disturbances with terahertz electromagnetic radiation at nitric oxide frequencies in albino rats under conditions of acute stress.

Terahertz electromagnetic irradiation at frequencies corresponding to NO molecular emission and absorption spectrum 150.176-150.664 GHz corrects disturbances in peripheral circulation typical of acute stress reaction in rats during acute immobilization stress.

[Use of terahertz electromagnetic radiation at nitric oxide frequencies for the correction of thyroid functional state during stress].

The influence of terahertz electromagnetic radiation at nitric oxide frequencies (150.176-150.664 Ghz) on the functional activity of rat thyroid gland subjected to acute immobilization stress has been studied. It is shown that terahertz radiation totally normalizes thyroid activity in stressed animals within 30 min after application.

Peculiarities of the effect of terahertz radiation at nitric oxide frequencies on gaseous and electrolyte composition of the blood in different types of stress.

We studied the effect of terahertz radiation at NO frequencies 150.176-150.664 GHz on gaseous and electrolyte composition of the blood in albino rats during stress. Partial or complete recovery of the studied parameters of blood gases and electrolytes in stressed animals was observed after 15- and 30-min terahertz irradiation at NO frequencies, respectively.

[Aggregative ability of thrombocytes and their receptor apparatus at a distant period after different operations on the injured spleen].

The aggregative ability of thrombocytes and the composition of the carbohydrate component of the thrombocyte glycoprotein receptors were studied in 126 patients after operations on the injured spleen within the terms of more than one year. It was found that organ-sparing operations and autolientransplantation in the injured spleen did not influence the changes of the thrombocyte aggregative properties at a remote postoperative period. Splenectomy results in an increased aggregative ability of thrombocytes at the expense of increased number of glycoprotein receptors containing D-mannose, N-acetyl-D-glucosamines, D-galactose, N-acetyl-D-glucosamines, N- acetylneuraminic acid and D-galactose.

Effects of terahertz irradiation at nitric oxide frequencies on intensity of lipoperoxidation and antioxidant properties of the blood under stress conditions.

The effects of terahertz irradiation at the nitric oxide frequencies (150.176-150.664 GHz) on the intensity of lipoperoxidation and antioxidant properties of the blood were examined on albino rats subjected to immobilization stress. This terahertz irradiation completely normalized LPO processes and functional activity of antioxidants in stressed rats.

Changes in the cytokine profile and reduced function of lymphocyte subpopulations in subacute tetrachloromethane poisoning.

Experiments on outbred albino rats showed that subacute poisoning with tetrachloromethane in a total dose of 1.0 LD50 appreciably decreased blood concentrations of cytokines (IFN-gamma, IL-2, IL-4, IL-6, IL-10), reduced the IFN-gamma/IL-4 ratio in comparison with the control, and suppressed the immune reactions, which attests to greater damage to Th1 compared to Th2 lymphocytes.

[Psychophysiological characteristics of patients with arterial hypertension under different social conditions].

The aim of the study was to compare psycho-physiological personality characteristics of patients with newly diagnosed arterial hypertension serving sentence in corrective-labour institutions and treated in a city hospital. In the first group, 36 men of the 612 had grade 1 or 2 essential arterial hypertension. Analysis of psycho-physiological characteristics showed that emotive behaviour and anxiety are the major personality traits hampering compensation of intrapsychic conflict of the psychosomatic type and promote neurotization and depression in subjects with arterial hypertension serving sentence in corrective-labour institutions.

[Penitentiary microenvironment as a risk factor of psychosomatic health (digest)].

This analytical survey shows that health status of jail prisoners in Russia as worldwide is strikingly different from that of the general population. The difference is accounted for by the concentration of socially dysadapted individuals in penitentiary institutions, conditions and relations facilitating the spread of certain infections in prisons. This problem is of importance for society at large because most prisoners sooner or later come back to the normal life and influence national health statistics. Moreover, penitentiary institutions constitute an important reserve of national health care systems since prevention and treatment of a large group of diseases among the prisoners facilitate the work of public health facilities serving the general population.

[Reduction of the immune responses and synthesis of cytokines associated with Th1 and Th2 lymphocyte function and their correction by polyoxidonium under conditions of subacute intoxication by organophosphorus compounds].

Experiments on Wistar rats showed that subacute poisoning by organophosphorus compounds dimethyldichlorovinyl phosphate (DDVF), malation, and dimethylparation (total dose, 1.0 LD50) suppresses both cell and humoral immune responses and significantly decreases the level of blood cytokines (IFNg, IL-4) and the IFNg/IL-4 ratio in comparison to the control, which is evidence for a greater lesion of Th1 cells in comparison to Th2 cells. The immunomodulator polyoxidonium administered for four days in a daily dose of 700 microg/kg under conditions of subacute intoxication with organophosphorus compounds restores the cell and humoral immune responses and the synthesis of cytokines.

[Specific changes of the thrombocyte aggregation function in acute pancreatitis].

On the basis of investigations of thrombocyte aggregation in 126 patients with acute pancreatitis it was shown that independent of the severity of the pancreatitis the aggregation function of thrombocytes decreased. The effective treatment resulted in its normalization not earlier than within 15 days.

Role of cholinergic and cytokine regulation of T cell function in stimulation and inhibition of immune reactions in intoxication by organophosphorus compounds in different doses.

Experiments on outbred albino rats showed that administration of acetylcholine and aceclidine in a dose of 0.1 LD50 for 3 days and of dimethyl dichlorovinyl phosphate (organophosphorus compound) in a single dose of 0.05 LD50 stimulated the function of Th1 and Th2 lymphocytes and cytokine production by these cells. Dimethyl dichlorovinyl phosphate in a single dose of 0.5 LD50 produced an opposite effect. Acetylcholine and aceclidine stimulated activity of acetylcholinesterase in T cells, while dimethyl dichlorovinyl phosphate in a single dose of 0.5 LD50 inhibited it. During acute intoxication, the organophosphorus compound, depending on the dose, can stimulate (acetylcholine effect) and inhibit the immune reactions (acetylcholinesterase inhibition of T cells).

Effect of high power terahertz irradiation on platelet aggregation and behavioral reactions of albino rats.

Intensive terahertz irradiation at the nitric oxide emission and absorption spectrum frequencies (150.176-150.664 GHz) applied for 60 min to male albino rats subjected to acute immobilization stress enhanced platelet aggregation and induced signs of depression.