Interocular Grouping in Perceptual Rivalry Localized with fMRI.

Bistable perception refers to a broad class of dynamically alternating visual illusions that result from ambiguous images. These illusions provide a powerful method to study the mechanisms that determine how visual input is integrated over space and time. Binocular rivalry occurs when subjects view different images in each eye, and a similar experience called stimulus rivalry occurs even when the left and right images are exchanged at a fast rate. Many previous studies have identified with fMRI a network of cortical regions that are recruited during binocular rivalry, relative to non-rivalrous control conditions (termed replay) that use physically changing stimuli to mimic rivalry. However, we show here for the first time that additional cortical areas are activated when subjects experience rivalry with interocular grouping. When interocular grouping occurs, activation levels broadly increase, with a slight shift towards right hemisphere lateralization. Moreover, direct comparison of binocular rivalry with and without grouping highlights strong focused activity in the intraparietal sulcus and lateral occipital areas, such as right-sided retinotopic visual areas LO1 and IP2, as well as activity in left-sided visual areas LO1, and IP0-IP2. The equivalent analyses for comparable stimulus (eye-swap) rivalry showed very similar results; the main difference is greater recruitment of the right superior parietal cortex for binocular rivalry, as previously reported. Thus, we found minimal interaction between the novel networks isolated here for interocular grouping, and those previously attributed to stimulus and binocular rivalry. We conclude that spatial integration (i.e,. image grouping/segmentation) is a key function of lateral occipital/intraparietal cortex that acts similarly on competing binocular stimulus representations, regardless of fast monocular changes.

Comparison of stimulus rivalry to binocular rivalry with functional magnetic resonance imaging.

When incompatible images are presented to each eye, a phenomenon known as binocular rivalry occurs in which the viewer's conscious visual perception alternates between the two images. In stimulus rivalry, similar perceptual alternations between rival images can occur even in the midst of fast image swapping between the eyes. Here, we used functional magnetic resonance imaging to directly compare brain activity underlying the two types of perceptual rivalry. Overall, we found that activity for binocular rivalry was always stronger and more widespread than that for stimulus rivalry-even more so during passive viewing conditions. In particular, the right superior parietal cortex and the right temporoparietal junction were prominently engaged for passive binocular rivalry. While both types of rivalry engaged higher tier visual regions such as the ventral temporal cortex during an active task, activity for stimulus rivalry was comparatively weak in early visual areas V1 to V3, presumably due to a weaker feed-forward signal due to both intraocular and interocular inhibition that may reduce effective contrast. In sum, only binocular rivalry produced perceptually vivid alternations, increased activation of the early visual cortex, and the coordinated engagement of dorsal stream regions, even when a task was not performed. These findings help characterize how stimulus rivalry fits within hierarchical models of binocular rivalry.