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1.
J Gen Intern Med ; 34(3): 387-395, 2019 03.
Article in English | MEDLINE | ID: mdl-30382471

ABSTRACT

BACKGROUND: Opioid overdose deaths occur in civilian and military populations and are the leading cause of accidental death in the USA. OBJECTIVE: To determine whether ECHO Pain telementoring regarding best practices in pain management and safe opioid prescribing yielded significant declines in opioid prescribing. DESIGN: A 4-year observational cohort study at military medical treatment facilities worldwide. PARTICIPANTS: Patients included 54.6% females and 46.4% males whose primary care clinicians (PCCs) opted to participate in ECHO Pain; the comparison group included 39.9% females and 60.1% males whose PCCs opted not to participate in ECHO Pain. INTERVENTION: PCCs attended 2-h weekly Chronic Pain and Opioid Management TeleECHO Clinic (ECHO Pain), which included pain and addiction didactics, case-based learning, and evidence-based recommendations. ECHO Pain sessions were offered 46 weeks per year. Attendance ranged from 1 to 3 sessions (47.7%), 4-19 (32.1%, or > 20 (20.2%). MAIN MEASURES: This study assessed whether clinician participation in Army and Navy Chronic Pain and Opioid Management TeleECHO Clinic (ECHO Pain) resulted in decreased prescription rates of opioid analgesics and co-prescribing of opioids and benzodiazepines. Measures included opioid prescriptions, morphine milligram equivalents (MME), and days of opioid and benzodiazepine co-prescribing per patient per year. KEY RESULTS: PCCs participating in ECHO Pain had greater percent declines than the comparison group in (a) annual opioid prescriptions per patient (- 23% vs. - 9%, P < 0.001), (b) average MME prescribed per patient/year (-28% vs. -7%, p < .02), (c) days of co-prescribed opioid and benzodiazepine per opioid user per year (-53% vs. -1%, p < .001), and (d) the number of opioid users (-20.2% vs. -8%, p < .001). Propensity scoring transformation-adjusted results were consistent with the opioid prescribing and MME results. CONCLUSIONS: Patients treated by PCCs who opted to participate in ECHO Pain had greater declines in opioid-related prescriptions than patients whose PCCs opted not to participate.


Subject(s)
Analgesics, Opioid/standards , Clinical Competence/standards , Drug Prescriptions/standards , Mentoring/standards , Military Medicine/standards , Physicians, Primary Care/standards , Adolescent , Adult , Analgesics, Opioid/therapeutic use , Cohort Studies , Education, Medical, Continuing/standards , Female , Humans , Male , Mentoring/methods , Middle Aged , Military Medicine/methods , Military Personnel , Pain Measurement/methods , Pain Measurement/standards , Physicians, Primary Care/education , Videoconferencing/standards , Young Adult
4.
Dig Dis Sci ; 59(3): 543-5, 2014 Mar.
Article in English | MEDLINE | ID: mdl-24549834

ABSTRACT

A 42-year-old woman developed epigastric abdominal pain and acutely elevated serum transaminase levels during a course of chemotherapy for breast cancer. Serum antibodies to hepatitis A, B and C were not identified initially, but subsequently a high hepatitis C viral load was detected. Ultrasonic imaging of the liver was normal. Serum transaminase elevations resolved within 2 months, and, after 6 months without therapy, the hepatitis C viral load became undetectable.


Subject(s)
Hepatitis C/diagnosis , Acute Disease , Adult , Female , Hepatitis C/immunology , Humans , Immunocompromised Host , Remission, Spontaneous
5.
N Engl J Med ; 364(23): 2199-207, 2011 Jun 09.
Article in English | MEDLINE | ID: mdl-21631316

ABSTRACT

BACKGROUND: The Extension for Community Healthcare Outcomes (ECHO) model was developed to improve access to care for underserved populations with complex health problems such as hepatitis C virus (HCV) infection. With the use of video-conferencing technology, the ECHO program trains primary care providers to treat complex diseases. METHODS: We conducted a prospective cohort study comparing treatment for HCV infection at the University of New Mexico (UNM) HCV clinic with treatment by primary care clinicians at 21 ECHO sites in rural areas and prisons in New Mexico. A total of 407 patients with chronic HCV infection who had received no previous treatment for the infection were enrolled. The primary end point was a sustained virologic response. RESULTS: A total of 57.5% of the patients treated at the UNM HCV clinic (84 of 146 patients) and 58.2% of those treated at ECHO sites (152 of 261 patients) had a sustained viral response (difference in rates between sites, 0.7 percentage points; 95% confidence interval, -9.2 to 10.7; P=0.89). Among patients with HCV genotype 1 infection, the rate of sustained viral response was 45.8% (38 of 83 patients) at the UNM HCV clinic and 49.7% (73 of 147 patients) at ECHO sites (P=0.57). Serious adverse events occurred in 13.7% of the patients at the UNM HCV clinic and in 6.9% of the patients at ECHO sites. CONCLUSIONS: The results of this study show that the ECHO model is an effective way to treat HCV infection in underserved communities. Implementation of this model would allow other states and nations to treat a greater number of patients infected with HCV than they are currently able to treat. (Funded by the Agency for Healthcare Research and Quality and others.).


Subject(s)
Community Health Services , Health Services Accessibility , Hepatitis C, Chronic/therapy , Physicians, Primary Care , Telemedicine , Videoconferencing , Academic Medical Centers , Adult , Analysis of Variance , Antiviral Agents/therapeutic use , Female , Hepacivirus/drug effects , Hepacivirus/genetics , Hepatitis C, Chronic/drug therapy , Hepatitis C, Chronic/virology , Humans , Interferon alpha-2 , Interferon-alpha/therapeutic use , Male , Medically Underserved Area , Middle Aged , New Mexico , Polyethylene Glycols/therapeutic use , Prospective Studies , Recombinant Proteins , Rural Health Services , Treatment Outcome
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