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Org Biomol Chem ; 4(21): 3960-5, 2006 Nov 07.
Article in English | MEDLINE | ID: mdl-17047876

ABSTRACT

Baylis-Hillman reactions of 2-nitrobenzaldehydes with various activated alkenes afford adducts that undergo reductive cyclisation to quinoline derivatives. The chemo- and regioselectivity of cyclisation appears to be influenced by the choice of both the substrate and the reagent system, and competing reactions have been observed.


Subject(s)
Models, Chemical , Quinolines/chemistry , Quinolines/chemical synthesis
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