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Folia Morphol (Warsz) ; 64(1): 1-8, 2005 Feb.
Article in English | MEDLINE | ID: mdl-15832263

ABSTRACT

Despite the variety of modern molecular techniques available, examination of foetal anatomy is still a fundamental part of teratological studies in evaluating the developmental toxicity of xenobiotics or other non-chemical factors. The article presents contemporary methods of embryotoxicity and foetotoxicity assessment. A single alizarin red S and double alcian blue followed by alizarin red S staining, as well as various methods of soft tissue examination are discussed.


Subject(s)
Fetus/anatomy & histology , Teratology , Alcian Blue/chemistry , Animals , Anthraquinones/chemistry , Bone and Bones/anatomy & histology , Bone and Bones/chemistry , Coloring Agents/chemistry , Female , Fetus/drug effects , Humans , Maternal Exposure , Rats , Teratology/methods , Xenobiotics/pharmacology
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