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Nat Prod Commun ; 12(1): 105-106, 2017 Jan.
Article in English | MEDLINE | ID: mdl-30549839

ABSTRACT

By alkylation of vanillin with 4,5-dichloro-3-chloromethylisothiazole the corresponding ether was synthesized. The latter was then reacted with p-toluidine to afford the corresponding azomethine. During the bioassays of synthesized isothiazolic derivatives of vanillin in mixtures with insecticides (imidacloprid and a-cypermethrin) a strong synergetic effect was observed.


Subject(s)
Benzaldehydes/pharmacology , Insecticides , Thiazoles/pharmacology , Animals , Coleoptera , Insecta , Insecticide Resistance , Larva , Neonicotinoids/pharmacology , Nitro Compounds/pharmacology , Pyrethrins/pharmacology , Toluidines/pharmacology
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