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1.
The synthesis of 3beta-hydroxyestr-4-en-17-one and 3beta-hydroxyandrost-4-en-17-one.
Klimstra, P D; Colton, F B.
Steroids ; 10(4): 411-24, 1967 Oct.
Article in English | MEDLINE | ID: mdl-6064262

Subject(s)
Androstanes/chemical synthesis , Estranes/chemical synthesis , Chemical Phenomena , Chemistry
2.
Steroidal 2,3-epithiospirolactones.
Klimstra, P D.
J Med Chem ; 10(3): 503-5, 1967 May 01.
Article in English | MEDLINE | ID: mdl-22185170
3.
Anabolic-androgenic activity of A-ring modified androstane derivatives. I. A comparison of parenteral activity.
Nutting, E F; Klimstra, P D; Counsell, R E.
Acta Endocrinol (Copenh) ; 53(4): 627-34, 1966 Dec.
Article in English | MEDLINE | ID: mdl-6012541

Subject(s)
Anabolic Agents/pharmacology , Androgens/pharmacology , Muscles/drug effects , Prostate/drug effects , Seminal Vesicles/drug effects , Animals , Biological Assay , Castration , Male , Rats
4.
Anabolic-androgenic activity of A-ring modified androstane derivatives. II. A comparison of oral activity.
Nutting, E F; Klimstra, P D; Counsell, R E.
Acta Endocrinol (Copenh) ; 53(4): 635-43, 1966 Dec.
Article in English | MEDLINE | ID: mdl-5953689

Subject(s)
Anabolic Agents/administration & dosage , Androgens/administration & dosage , Muscles/drug effects , Prostate/drug effects , Seminal Vesicles/drug effects , Animals , Biological Assay , Castration , Male , Methyltestosterone , Organ Size , Rats
5.
Anabolic agents. A-ring oxygenated androstane derivatives.
Klimstra, P D; Zigman, R; Counsell, R E.
J Med Chem ; 9(6): 924-9, 1966 Nov.
Article in English | MEDLINE | ID: mdl-5972054

Subject(s)
Testosterone , Anal Canal , Animals , Castration , Chemistry, Organic , Male , Muscles/drug effects , Organ Size/drug effects , Organic Chemistry Phenomena , Prostate/drug effects , Rats , Seminal Vesicles/drug effects , Testosterone/pharmacology
6.
Chemical and biological properties of some 17-substituted estradiol derivatives.
Counsell, R E; Klimstra, P D; Elton, R L; Nutting, E F.
J Med Chem ; 9(5): 689-92, 1966 Sep.
Article in English | MEDLINE | ID: mdl-5969040

Subject(s)
Endometrium/drug effects , Estradiol , Estradiol/pharmacology , Progestins/pharmacology , Uterus/drug effects , Vagina/drug effects , Animals , Chemistry, Organic , Estradiol/administration & dosage , Female , Organic Chemistry Phenomena , Progesterone/pharmacology , Rabbits , Rats
7.
Anabolic agents. 2,3-Epithioandrostane derivatives.
Klimstra, P D; Nutting, E F; Counsell, R E.
J Med Chem ; 9(5): 693-7, 1966 Sep.
Article in English | MEDLINE | ID: mdl-5969041

Subject(s)
Anabolic Agents , Anabolic Agents/pharmacology , Muscles/drug effects , Prostate/drug effects , Seminal Vesicles/drug effects , Anabolic Agents/administration & dosage , Anal Canal , Animals , Castration , Chemistry, Organic , Male , Methyltestosterone/pharmacology , Organ Size/drug effects , Organic Chemistry Phenomena , Rats , Testosterone/pharmacology
8.
The synthesis of some 2,3-epithio-5-alpha-pregnanes.
Klimstra, P D.
J Med Chem ; 9(5): 781-2, 1966 Sep.
Article in English | MEDLINE | ID: mdl-5969058

Subject(s)
Sulfides , Thiocyanates , Animals , Chemistry, Organic , Organic Chemistry Phenomena , Rats , Sulfides/pharmacology , Thiocyanates/pharmacology
9.
The estrogenic and deciduogenic properties of some estra-1,3,5(10)triene-3,17-beta-diol derivatives.
Elton, R L; Counsell, R E; Klimstra, P D; Nutting, E F.
Experientia ; 22(7): 437-9, 1966 Jul 15.
Article in English | MEDLINE | ID: mdl-5964094

Subject(s)
Estrogens/pharmacology , Progestins/pharmacology , Uterus/drug effects , Vagina/drug effects , Animals , Biological Assay , Ethynodiol Diacetate/pharmacology , Female , Mice , Organ Size , Rabbits , Rats , Vagina/metabolism , Vaginal Smears
10.
Hypocholesterolemic agents. VI. A- and B-ring-modified azacholesterols.
Klimstra, P D; Ranney, R E; Counsell, R E.
J Med Chem ; 9(3): 323-6, 1966 May.
Article in English | MEDLINE | ID: mdl-5960897

Subject(s)
Anticholesteremic Agents/pharmacology , Animals , Anticholesteremic Agents/administration & dosage , Chemical Phenomena , Chemistry , Chemistry, Organic , Male , Organic Chemistry Phenomena , Rats
11.
Induction of deciduoma in rabbits without uterine trauma by treatment with ethynodiol diacetate: a synthetic progestogen.
Elton, R L; Klimstra, P D; Colton, F B.
Proc Soc Exp Biol Med ; 121(4): 1194-6, 1966 Apr.
Article in English | MEDLINE | ID: mdl-5949275

Subject(s)
Contraceptives, Oral/pharmacology , Decidua , Progestins/pharmacology , Pseudopregnancy , Animals , Drug Synergism , Ethynodiol Diacetate/pharmacology , Female , Mestranol/pharmacology , Pregnancy , Pregnancy, Animal , Rabbits
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