[Regular thermal waves in female mammary glands].

During experimental studies of thermal regime of female mammary glands tissues the existence of periodic thermal waves was discovered. At the same time, the space-amplitude relief of such waves can mask the space-amplitude relief of the thermal profile, projected to the skin surface of mammary glands by tumor, hidden in the thickness of the gland. The phenomenon observed would be taken into account upon diagnosing pathological states of mammary glands.

[Ultraminiature electrochemical and photoelectric current sources and their possible use for controlled induction of immune system activity and in other medical applications].

The possibility of producing microparticles (10-1000 nm) suitable for the introduction into biological cells and tissues and producing the electrical field and electrical currents around them due to electrochemical and photoelectric processes is discussed. A number of phenomena related to antitumor immunity are discussed, and several hypotheses to explain them are invoked. Among them is the hypothesis that the antitumor activity of the immune system may be associated with some agents that are phagocytized by the cells of the macrophage series and promote their activation. Presumably, cell activation is triggered by the damage to phagosomes caused by the phagocytized agent. It is suggested to use for cell activation an artificial agent consisting of the above-mentioned electrically active microscopic particles. For example, it may consist of microscopic particles of semiconductor with zones of n- and p-type conductivity. Such particles act as microscopic photoelectric cells: when exposed to optical radiation, they generate a potential difference, which causes disruption and damage of phagosome membranes and results in the activation of immune cells.

[A method for reconstruction of pathological changes in the volume of a living body]. / Metod rekonstruktsii uchastkov patologii v ob''eme zhivogo ob''ekta.

A new method of contact thermography (intrograph) was developed. The method allows one to establish the temperature in any region of the body. The computer program provides an uninvasive and safe way of comparison of thermograms in time. The obviously known biomedical parameters allow one to locate and characterize pathology foci. The accuracy of one temperature measurement is not worse than 0.01 deg at a measurement time of about one second.

[Cell sorting using magnetoliposomes]. / O vozmozhnosti sortirovki kletok s pomoshch'iu magnitoliposom.

Liposome-entrapped ferromagnetic particles are bound to the surface of L cells. A system of circular magnets is capable of concentrating magnetoliposome-bound cells, separating them from free cells. Antibodies associated with magnetoliposomes enable to concentrate selectively the target cells. Magnetoliposomes could be used for developing a new cell-sorting system.