ABSTRACT
OBJECTIVE: To determine neurophysiological characteristics of patients with long-term follow up (>20 years) and to find correlations between neurophysiological parameters and clinical features of schizophrenia. MATERIAL AND METHODS: The patients were divided into three groups: with predomination of personality changes (group 1, n=17), with negative disorders (group 2, n=23) and with positive and negative disorders (group 3, n=40). A psychopathological method and electroencephalography with evoked potentials testing were used. RESULTS AND CONCLUSION: In group 3, the statistically significant higher frequencies of theta-rhythm and lower of alpha-rhythm were found. Also, theta frequency correlated with PANSS positive scores. The significant intergroup differences by auditory oddball P300 were lacked. The findings are discussed in view of the hypothesis of theta-rhythm as a marker of hippocampal-prefrontal connectivity.
Subject(s)
Schizophrenia/physiopathology , Adolescent , Electroencephalography , Event-Related Potentials, P300 , Evoked Potentials, Auditory , Follow-Up Studies , Humans , Theta RhythmABSTRACT
AIM: To search for neurophysiological predictors of the effectiveness of rhythmic transcranial magnetic stimulation (rTMS) of the left dorsolateral prefrontal cortex in patients with depressive disorder of various nosology. MATERIAL AND METHODS: Thirty-four young male patients with protracted treatment resistant depression were studied using psychopathological, psychometric methods and encephalography. A search for predictors of therapeutic efficacy was carried out in a wide range of neurophysiological indicators using different high-frequency rTMS protocols (10 Hz and 20 Hz).. RESULTS AND CONCLUSION: The most significant changes were obtained using rTMS with a frequency of 20 Hz. A favorable effect of treatment was correlated with higher spectral power of the alpha- and beta 1-rhythm bands in EEG.
Subject(s)
Depressive Disorder/therapy , Transcranial Magnetic Stimulation , Adolescent , Humans , Male , Prefrontal Cortex , Treatment OutcomeABSTRACT
The authors give a description of acute complications when delivering urgent and emergency pharmacotherapy. The authors examined normative legal basis, regulating urgent and emergency aid delivery at the army level of the medical service of the Armed Forces of the Russian Federation, and determine the list of medications. Comparative description of pharmacotherapy of acute complications of diabetes is given and determined its possibilities.
Subject(s)
Diabetes Complications/drug therapy , Emergency Medical Services , Military Medicine , Acute Disease , Emergency Medical Services/methods , Emergency Medical Services/organization & administration , Emergency Medical Services/standards , Female , Humans , Male , Military Medicine/methods , Military Medicine/organization & administration , Military Medicine/standards , RussiaABSTRACT
Authors presented a historical summary about formation and development of military formulary system and quantitative and qualitative characteristics of the fifth edition of the Drug formulary. The new Drug formulary is a list of drugs developed on the basis of multi-criteria choice of optimal alternatives according clinical and pharmacoeconomic effectiveness, costs with due regard to possible pharmacological support for troops. The fifth edition of the Drug Formulary fully covers medical and social demands of military servicemen, of military retirees and members of their families for the effective drugs during the treatment of socially important and common aliments within the framework of established government guarantee.
