[Diagnostic value of sleep deprivation as the EEG activation method in diagnosis of epilepsy in developmental age]. / Wartosc diagnostyczna deprywacji snu jako metody aktywacji EEG w rozpoznawaniu padaczki w wieku rozwojowym.

The paper presented the significance of EEG activation in diagnosing epilepsy in children and adolescents. EEG records of 108 patients between 3-19 years of age with the occurrence of various types of paroxysmal disorders who were admitted to Chair and Department of Developmental Neurology University of Medical Sciences in Poznan were analysed. Standard EEG was administered to all children twice: the first examination at rest with hyperventilation (HV) and photostimulation (FS) and the second one after total or partial sleep deprivation (DS). At awaking state normal records were stated in 57% of cases, in 15% paroxysmal changes in HV or FS appeared, in the rest of cases (28%) generalised paroxysmal disorders, localised changes, lateralised or diffused were noted. Among EEG activation methods DS occurred to be the most effective after it, 52 patients (48%) were diagnosed for generalised paroxysmal changes, 20% for localised, 3% lateralised and for 6% for diffused changes. Normal EEG were recorded in 22% of examined children and adolescents. The epilepsy were diagnosed in 59 (55%) of patients mostly with generalised seizures (28) partial secondarily generalised (16) and partially complex (11). In 49 (45%) children were diagnosed with other paroxysmal disorders.

[Oxcarbazepine in the treatment of drug-resistant epilepsy in children and adolescents: preliminary study]. / Okskarbazepina w leczeniu padaczki lekoopornej u dzieci i mlodziezy--doniesienie wstepne.

A comparative study was conducted to evaluate the efficacy and tolerability of oxcarbazepine administration in patients with a diagnosed intractable epilepsy with simple partially and complex seizures secondarily generalised. There were 12 patients aged between 2-23 treated in Outpatients' Neurological Department for Children and Adolescents in Poznan. Oxcarbazepine was applied as an add-on therapy in all patients. The drug was administered in 3 daily dose. The doses of oxcarbazepine were evaluated as well as the occurrence of adverse effects was recorded. Four patients presented over 50% reduction of seizures. During the whole period of observation there was no occurrence of adverse effects associated with the inclusion of oxcarbazepine as add-on drug.