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Cancer Detect Prev ; 15(3): 189-97, 1991.
Article in English | MEDLINE | ID: mdl-1711925

ABSTRACT

The levels of selected acute phase proteins (APP) and of tumor-associated suppressive E-receptor factor (SER) were determined in sequential serum specimens from (1) cancer patients under treatment with autolymphocyte therapy (ALT) or plasmapheresis, (2) patients with acute infections, (3) patients with autoimmune disorders, and (4) other nonmalignant diseases. The absolute serum levels of APP, including SER, and their patterns of change over time are shown to differ significantly between cancer and non-cancer patients. The absolute levels of APP and the patterns of change over time appear to be useful indicators of immune status and predictors of antitumor response to autolymphocyte (and possibly other anti-cancer) therapy.


Subject(s)
Acute-Phase Proteins/analysis , Carcinoma, Renal Cell/blood , Immunosuppressive Agents/blood , Kidney Neoplasms/blood , Neoplasms/blood , Adult , Aged , Aged, 80 and over , Autoimmune Diseases/blood , Carcinoma, Renal Cell/therapy , Female , Humans , Immunotherapy , Infections/blood , Kidney Neoplasms/therapy , Male , Middle Aged , Neoplasms/therapy , Plasmapheresis , Reference Values , Serum Albumin/metabolism
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