ABSTRACT
An epidemiological survey of hereditary ataxias and paraplegias was conducted in Molise, a region of Italy (335, 211 inhabitants on 1 January 1989). Total prevalence was 7.5 x 10(-5) inhabitants (95% confidence limits 4.8-11.1). There were 7 patients with Friedreich's disease, 5 with early onset cerebellar ataxia with retained tendon reflexes, 4 with ataxia-telangiectasia, 9 with hereditary spastic paraplegias (2 autosomal dominant and 7 autosomal recessive cases). There was no patient with autosomal dominant cerebellar ataxia.
Subject(s)
Ataxia/epidemiology , Paraplegia/epidemiology , Adolescent , Adult , Ataxia/classification , Ataxia/genetics , Child , Child, Preschool , Female , Humans , Infant , Italy/epidemiology , Male , Middle Aged , Paraplegia/classification , Paraplegia/genetics , PrevalenceABSTRACT
Hemi-infarction of the medulla causes the clinical constellation of symptoms and signs of both the lateral and medial medullary syndromes and nearly always results from occlusion of an intracranial vertebral artery. In the case reported here, with a clinical diagnosis of hemimedullary syndrome, the expected infarction was imaged by magnetic resonance. A review of the literature confirms that the hemimedullary syndrome, in which both medial and lateral syndromes occur simultaneously, is extremely rare, since it yielded only two previous cases with adequate anatomical confirmation.
Subject(s)
Cerebral Infarction/diagnosis , Medulla Oblongata , Adult , Angiography, Digital Subtraction , Brain Stem/physiopathology , Cerebral Infarction/diagnostic imaging , Cerebral Infarction/physiopathology , Evoked Potentials, Auditory , Follow-Up Studies , Humans , Magnetic Resonance Imaging , Male , Vertebral Artery/diagnostic imagingSubject(s)
Aprotinin , Factor XIII , Fibrin , Fibrinogen , Microsurgery , Thrombin , Tissue Adhesives , Vascular Surgical Procedures , Anastomosis, Surgical , Animals , Drug Combinations , Fibrin Tissue Adhesive , Male , Rabbits , Rats , Rats, Inbred Strains , SuturesABSTRACT
We report a further case of retarded contralateral hemiplegia syndrome after herpes zoster ophthalmicus in which the motor deficit was caused by an ischemic infarction in the territory supplied by the anterior choroidal artery. We discuss the clinical and physiopathogenetic features of the case and consider the computed tomographic and neurological patterns of anterior choroidal infarction.
Subject(s)
Cerebral Infarction/etiology , Choroid Plexus/physiopathology , Hemiplegia/etiology , Herpes Zoster Ophthalmicus/complications , Aged , Cerebral Infarction/diagnostic imaging , Choroid Plexus/diagnostic imaging , Humans , Male , Tomography, X-Ray ComputedABSTRACT
The Authors report a rare case of traumatic aneurysm of the internal carotid artery observed in a 19-year-old man after a car accident. The aneurysm was recognized by cerebral angiography performed immediately after trauma and clipped to avoid delayed rupture. The literature on traumatic aneurysms is reviewed.
Subject(s)
Carotid Artery Injuries , Craniocerebral Trauma/complications , Intracranial Aneurysm/etiology , Adult , Humans , Intracranial Aneurysm/diagnostic imaging , Intracranial Aneurysm/surgery , Male , RadiographyABSTRACT
An echocardiographic study of 50 patients with cerebral infarction confirm the importance of this technique in the diagnosis of cerebral ischaemia originating in a cardiac embolism, an importance that has already been underlined by others. The particular value of this technique in young patients in relation to possible treatment is also pointed out.
Subject(s)
Echocardiography , Embolism/diagnosis , Heart Diseases/diagnosis , Ischemic Attack, Transient/diagnosis , Adult , Aged , Cerebral Infarction/diagnosis , Cerebral Infarction/etiology , Embolism/complications , Evaluation Studies as Topic , Heart Diseases/complications , Humans , Ischemic Attack, Transient/etiology , Middle AgedABSTRACT
The Authors, on the base of Vackeneim's pathogenetic hypothesis about a case of post-traumatic bone bridges of the spine, describe three cases observed and examine the etiopathogenesis of this extremely rare pathology.
Subject(s)
Lumbar Vertebrae/injuries , Synostosis/etiology , Humans , Spinal Diseases/diagnostic imaging , Spinal Diseases/surgery , Synostosis/diagnostic imaging , Synostosis/surgery , Tomography, X-Ray ComputedABSTRACT
The use of F.E.S. in motor rehabilitation should be reserved for cases of central neurological lesions. F.E.S. tends to improve gait, reduce spasticity and improve the transfer of cortical information from the peripheral system. The treatment exploits the possibilities of reprogramming movement by developing new motor circuits and where possible restoring lost movements.
Subject(s)
Electric Stimulation Therapy , Paralysis/therapy , Electrodes , Electrodes, Implanted , Gait , Humans , Muscle Contraction , Muscle Spasticity/therapySubject(s)
Brain Injuries/therapy , Catheterization/adverse effects , Infusions, Parenteral/adverse effects , Parenteral Nutrition, Total/adverse effects , Parenteral Nutrition/adverse effects , Sepsis/etiology , Shock, Septic/etiology , Brain Injuries/drug therapy , Humans , Pharmaceutical Preparations/administration & dosage , Subclavian VeinSubject(s)
Brain Diseases/drug therapy , Catheterization/adverse effects , Parenteral Nutrition, Total/adverse effects , Parenteral Nutrition/adverse effects , Sepsis/etiology , Thrombophlebitis/etiology , Brain Injuries/drug therapy , Humans , Infusions, Parenteral/adverse effects , Pharmaceutical Preparations/administration & dosageABSTRACT
An assessment was made of the blood lipid pattern in a group of patients in critical situations subjected to T.P.N. with a mixed calorie intake (sugars, lipids, amino acids). It was found that the pronounced previous deficiency was corrected in a significantly shorter period, and that despite the large load on calories in the form of fats there were no changes worthy of note in the body fluids. Serial determination of lipoproteins before, during and after T.P.N. substantiated the clinical findings. Lab checks, within the limits set by intuitive variations, did not reveal alterations with a pathological meaning, for the very reason that they were not linked to organic enzyme and hormone deficiencies, but were positive changes attributable to the temporary exogenous input.