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J Bone Joint Surg Br ; 89(3): 382-7, 2007 Mar.
Article in English | MEDLINE | ID: mdl-17356155

ABSTRACT

We reviewed 234 benign solitary schwannomas treated between 1984 and 2004. The mean age of the patients was 45.2 years (11 to 82). There were 170 tumours (73%) in the upper limb, of which 94 (40%) arose from the brachial plexus or other nerves within the posterior triangle of the neck. Six (2.6%) were located within muscle or bone. Four patients (1.7%) presented with tetraparesis due to an intraspinal extension. There were 198 primary referrals (19 of whom had a needle biopsy in the referring unit) and in these patients the tumour was excised. After having surgery or an open biopsy at another hospital, a further 36 patients were seen because of increased neurological deficit, pain or incomplete excision. In these, a nerve repair was performed in 18 and treatment for pain or paralysis was offered to another 14. A tender mass was found in 194 (98%) of the primary referrals. A Tinel-like sign was recorded in 155 (81%). Persistent spontaneous pain occurred in 60 (31%) of the 194 with tender mass, impairment of cutaneous sensibility in 39 (20%), and muscle weakness in 24 (12%). After apparently adequate excision, two tumours recurred. No case of malignant transformation was seen.


Subject(s)
Neurilemmoma/surgery , Peripheral Nervous System Neoplasms/surgery , Adolescent , Adult , Aged , Aged, 80 and over , Biopsy , Bone Neoplasms/pathology , Bone Neoplasms/physiopathology , Bone Neoplasms/surgery , Brachial Plexus Neuropathies/pathology , Brachial Plexus Neuropathies/physiopathology , Brachial Plexus Neuropathies/surgery , Child , Female , Humans , Male , Middle Aged , Muscle Neoplasms/pathology , Muscle Neoplasms/physiopathology , Muscle Neoplasms/surgery , Neurilemmoma/pathology , Neurilemmoma/physiopathology , Pain/physiopathology , Peripheral Nervous System Neoplasms/pathology , Peripheral Nervous System Neoplasms/physiopathology , Postoperative Complications , Treatment Outcome
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