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1.
BMC Res Notes ; 11(1): 325, 2018 May 21.
Article in English | MEDLINE | ID: mdl-29784021

ABSTRACT

OBJECTIVE: The Eat Well Move More (EWMM) family and child weight management service is a 12-week intervention integrating healthy eating and physical activity education and activities for families and children aged 4-16. EWMM service providers identified low uptake 12 months prior to the evaluation. The aims of this study were to describe referral practices and pathways into the service to identify potential reasons for low referral and uptake rates. RESULTS: We conducted interviews and focus groups with general practitioners (GPs) (n = 4), school nurses, and nursing assistants (n = 12). Data were analysed using thematic analysis. School nurses highlighted three main barriers to making a referral: parent engagement, child autonomy, and concerns over the National Child Measurement Programme letter. GPs highlighted that addressing obesity among children is a 'difficult conversation' with several complex issues related to and sustaining that difficulty. In conclusion, referral into weight management services in the community may persistently lag if a larger and more complex tangle of barriers lie at the point of school nurse and GP decision-making. The national prevalence of, and factors associated with this hesitation to discuss weight management issues with parents and children remains largely unknown.


Subject(s)
Exercise , Family , Health Communication , Health Education/methods , Health Knowledge, Attitudes, Practice , Pediatric Obesity/therapy , School Health Services , Weight Reduction Programs/methods , Adolescent , Child , Child, Preschool , Female , Humans , Male , Qualitative Research
2.
J Bone Miner Res ; 25(1): 32-40, 2010 Jan.
Article in English | MEDLINE | ID: mdl-19580461

ABSTRACT

Moderate to severe osteogenesis imperfecta is associated with multiple fractures in childhood. There are no published data regarding the effects of third-generation bisphosphonates in these children. This randomized study investigated which of three different doses of risedronate was most effective in reducing fracture incidence. We randomly assigned 53 children with moderate to severe osteogenesis imperfecta to receive 0.2, 1, or 2 mg/kg per week of risedronate. We assessed safety, fracture incidence, and bone measurement outcomes at 3, 6, 12, 18, and 24 months. At 24 months, 69% of children assigned 0.2 mg/kg per week had had new fractures compared with 44% receiving 1 mg/kg per week and 75% receiving 2 mg/kg per week. Poisson regression with age and prior fracture as covariates showed that there was no difference in incident nonvertebral fracture between groups. Fracture rate diminished in each group during the trial compared with previous the 2 years (p = .005). Lumbar spine bone mineral density increased significantly (p = .009) only in the 2 mg/kg per week group. Long bone bowing deformities reduced more in children receiving 1 or 2 mg/kg per week of risedronate [odds ratio (OR) 0.67, 95% confidence interval (CI) 0.48-0.93 per unit increase in risedronate dose, p = .015]. There were no serious adverse events. Bone mass increased and bowing deformities reduced with increasing risedronate dose. Children suffered fewer fractures irrespective of risedronate dose. The most appropriate dose of risedronate for children with moderate to severe osteogenesis imperfecta in this study was 2 mg/kg per week.


Subject(s)
Bone Density Conservation Agents/administration & dosage , Bone Density Conservation Agents/therapeutic use , Etidronic Acid/analogs & derivatives , Osteogenesis Imperfecta/drug therapy , Osteogenesis Imperfecta/pathology , Absorptiometry, Photon , Administration, Oral , Adolescent , Age Determination by Skeleton , Bone Density Conservation Agents/adverse effects , Child , Child, Preschool , Demography , Dose-Response Relationship, Drug , Etidronic Acid/administration & dosage , Etidronic Acid/adverse effects , Etidronic Acid/therapeutic use , Fractures, Bone/drug therapy , Fractures, Bone/epidemiology , Humans , Incidence , Risedronic Acid , Spine/pathology , Treatment Outcome , United Kingdom/epidemiology
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