1.
Ann Plast Surg
; 45(4): 438-41, 2000 Oct.
Article
in English
| MEDLINE
| ID: mdl-11037169
ABSTRACT
Docetaxel (Taxotere) is a relatively new antineoplastic agent that is proving to be clinically useful in the treatment of a number of major solid tumors, including breast, ovarian, lung, and prostate carcinoma. Common systemic toxicities include neutropenia, alopecia, nausea, and vomiting. The authors report 5 patients (age range, 54-89 years) who experienced extravasation injuries with dramatic clinical presentations during peripheral intravenous administration of docetaxel. The authors did not find any other reported series of docetaxel extravasation in an extensive literature review. They present these 5 patients and provide treatment recommendations.
Subject(s)
Antineoplastic Agents, Phytogenic/adverse effects , Edema/etiology , Erythema/etiology , Extravasation of Diagnostic and Therapeutic Materials/therapy , Paclitaxel/analogs & derivatives , Paclitaxel/adverse effects , Taxoids , Aged , Aged, 80 and over , Antineoplastic Agents, Phytogenic/administration & dosage , Carcinoma, Non-Small-Cell Lung/drug therapy , Docetaxel , Hand , Humans , Infusions, Intravenous , Lung Neoplasms/drug therapy , Male , Middle Aged , Paclitaxel/administration & dosage , Prostatic Neoplasms/drug therapy , Prostatic Neoplasms/secondary
2.
Bull Schweiz Akad Med Wiss
; 23(1): 98-105, 1967 Aug.
Article
in English
| MEDLINE
| ID: mdl-4860569