ABSTRACT
Female animals tolerate trauma and hemorrhage better than male animals AND Estrogen has rapid nongenomic effects that protect organs from damage and attenuate insult-induced inflammation MOREOVER The survival deficit from trauma and hemorrhage produced in ovariectomized female animals is repaired with administration of exogenous estrogen AND Women survive injury, sepsis, and trauma-hemorrhage-induced hypoxemia/reperfusion better than men THEREFORE Women rule ... in survival after trauma, thus, men would benefit from being more like women.
Subject(s)
Estradiol/therapeutic use , Estrogens/metabolism , Reperfusion Injury/mortality , Sepsis/mortality , Sex Characteristics , Animals , Estradiol/pharmacology , Estrogens/therapeutic use , Evidence-Based Medicine , Female , Heart/drug effects , Humans , Lung/drug effects , Male , Reperfusion Injury/metabolism , Sepsis/metabolismABSTRACT
The American College of Surgeons Committee on Trauma's Advanced Trauma Life Support Course is currently taught in 50 countries. The 8th edition has been revised following broad input by the International ATLS subcommittee. Graded levels of evidence were used to evaluate and approve changes to the course content. New materials related to principles of disaster management have been added. ATLS is a common language teaching one safe way of initial trauma assessment and management.
