ABSTRACT
In systemic lupus erythematosus (SLE), the central nervous system (CNS) produces numerous and varying clinical disorders. A 14-year-old girl with the features of cerebral involvement in SLE is presented. The development of diabetes insipidus (DI), which responded to desmopressin, was an interesting finding in this case. Therapy consisting of high-dose methylprednisolone combined with cyclophosphamide was effective in improving the symptoms as well as the DI.
Subject(s)
Diabetes Insipidus/etiology , Lupus Erythematosus, Systemic/complications , Adolescent , Anti-Inflammatory Agents/therapeutic use , Cyclophosphamide/therapeutic use , Deamino Arginine Vasopressin/therapeutic use , Diabetes Insipidus/drug therapy , Drug Therapy, Combination , Female , Humans , Hypoglycemic Agents/therapeutic use , Immunosuppressive Agents/therapeutic use , Methylprednisolone/therapeutic useABSTRACT
Meckel syndrome in twins is presented. Although several families have been reported as having this syndrome in more than one member, this is the first instance that twins having this disorder have been reported. We wish to emphasize the importance of genetic counselling in such a case in which prenatal diagnosis is possible.
