ABSTRACT
Primary mucinous carcinoma of the skin is an extremely rare adnexal tumor that is thought to originate from eccrine sweat glands. The neoplasm usually arises on the head and neck, with the most commonly involved area being the periorbital region. The tumor is typically a solitary, asymptomatic nodule, cyst, or ulcer that is slow growing with low metastatic potential. However, post-excisional local recurrence is common, affecting up to 36 percent of patients. Since primary mucinous carcinoma of the skin is such a rare neoplasm (fewer than 130 cases have been reported to date), a complete workup should be conducted to rule out other internal malignancies that may metastasize to the skin. We report a case of primary mucinous carcinoma of the skin, and discuss the clinical presentation, histology, treatment, course, and prognosis.
Subject(s)
Adenocarcinoma, Mucinous/pathology , Facial Neoplasms/pathology , Skin Neoplasms/pathology , Adenocarcinoma/pathology , Adenocarcinoma/surgery , Eyebrows , Humans , Male , Middle Aged , Neoplasms, Second Primary/pathology , Neoplasms, Second Primary/surgery , Prostatic Neoplasms/pathology , Prostatic Neoplasms/surgeryABSTRACT
We report what we believe to be the first documentation of a patient with both cold urticaria and mycosis fungoides. The patient described a marked worsening of his long-standing lesions of mycosis fungoides at the same time as the onset of cold sensitivity. We believe this suggests a possible association between these 2 rare diseases.
Subject(s)
Cold Temperature , Mycosis Fungoides/complications , Skin Neoplasms/complications , Urticaria/complications , Adult , Humans , Male , Urticaria/etiologyABSTRACT
BACKGROUND: Local anesthesia is an integral aspect of cutaneous surgery. Its effects provide a reversible loss of sensation in a limited area of skin, allowing dermatologists to perform diagnostic and therapeutic procedures safely, with minimal discomfort and risk to the patient. OBJECTIVE: This article discusses the application of local anesthetics in dermatologic surgery through a brief review of the mechanism of local anesthetic activity, classification of local anesthetics, and adverse effects. The discussion will focus on the different methods of administration and techniques that may make the administration less painful to patients. METHODS: An evaluation of the literature, as well as clinical experience in the administration of local anesthetics provide the basis for this review. CONCLUSION: Local anesthesia provides a safe and effective means of decreasing patient's sensitivity to pain. Because of its critical importance to the field of dermatology, a working knowledge of local anesthetics is necessary for optimal use of these agents.
