ABSTRACT
BACKGROUND: Recent studies have demonstrated a relationship between insulin resistance (IR) and type 2 diabetes mellitus (T2DM). The aim of this study was to determine the prevalence of T2DM among patients with liver disease. METHODS: A retrospective study was performed by examining the charts of patients who presented with a diagnosis of liver disease at a university hospital between January 2006 and April 2010. RESULTS: Liver disease was found in 129 patients. The most prevalent liver disease was cirrhosis, with 61 patients (47.2%), 44 patients had hepatitis C virus (34.1%) and 28 patients had hepatocellular carcinoma (21.7%). T2DM was diagnosed in 30 patients, 18 of whom were male (18/60; 30%) and 12 of whom were female (12/69; 17.4%). Only liver cirrhosis was significantly related to T2DM (21 of 61 patients; 34.4%, p < 0.004). CONCLUSIONS: The prevalence of T2DM among patients with liver disease (23.2%) is well established and similar to that reported in Western and some Eastern countries.
Subject(s)
Carcinoma, Hepatocellular/epidemiology , Diabetes Mellitus, Type 2/epidemiology , Liver Cirrhosis/epidemiology , Liver Neoplasms/epidemiology , Adult , Age Distribution , Aged , Chronic Disease , Fatty Liver/epidemiology , Female , Hepatitis C, Chronic/epidemiology , Humans , Male , Mexico/epidemiology , Middle Aged , Non-alcoholic Fatty Liver Disease , Prevalence , Retrospective StudiesABSTRACT
Hepatitis C virus is one of the most common causes of chronic liver disease and one of the principal indications for liver transplantation. The prevalence and incidence worldwide is variable, although there may be some similarities among different regions. Worldwide prevalence has been estimated around 3.1% or 170 million infected people. The Latin America region has one of the lowest prevalence around the world with an overall prevalence estimated around 1.23%, nevertheless it varies from country to country and even between regions of the same country. Although the principal route of transmission continues being blood transfusion, the epidemiological change around the world is affecting our region, increasing the virus transmission among intravenous drugs users. Also in Latin America the most prevalent genotype is 1 different from other regions like Africa and Asia. The knowledge of epidemiology of Hepatitis C in our region is basic for the prevention and treatment of this arising disease, and further research with greater general population based studies must be carried out.