ABSTRACT
We found very high concentrations of vascular endothelial growth factor, hepatic growth factor, and epidermal growth factor in early breast milk samples obtained from healthy mothers of term infants. This is the first report of simultaneous measurements of three major gastrointestinal trophic substances in human milk.
Subject(s)
Epidermal Growth Factor/analysis , Hepatocyte Growth Factor/analysis , Milk, Human/chemistry , Vascular Endothelial Growth Factor A/analysis , Enzyme-Linked Immunosorbent Assay , Female , HumansSubject(s)
Abnormalities, Drug-Induced , Bone and Bones/abnormalities , Magnesium Sulfate/administration & dosage , Magnesium Sulfate/adverse effects , Tocolytic Agents/administration & dosage , Tocolytic Agents/adverse effects , Female , Humans , Infant , Infant, Newborn , Male , Pre-Eclampsia/drug therapy , Pregnancy , Pregnancy Trimester, Second , Tocolysis/adverse effects , Triplets , TwinsABSTRACT
The authors report serial brain MR findings from a 2-year-old girl with rotavirus encephalopathy. The lesion in the splenium of the corpus callosum showed restricted proton diffusion, suggesting local cytotoxic edema. Diffusion-weighted images demonstrated the lesion more conspicuously than other techniques, such as fluid-attenuated inversion-recovery and T1- and T2-weighted images. The findings were reversible on follow-up MRI obtained 4 days later. Diffusion-weighted MRI is a potentially useful method for detecting early changes of rotavirus encephalopathy, although the mechanism of the restricted diffusion is not clearly identified.