Proposition of a New POLA Index to Assess the Immunomodulatory Properties of the Diet and Its Relationship with the Gut Microbiota, Using the Example of the Incidence of COVID-19 in a Group of People without Comorbidities.

A rise in the incidence of infections with severe acute respiratory syndrome coronavirus 2 has sparked the search for protective strategies against the new pathogen. It is known that individual food components can interact with different immune cells, modulating the immune response of the body. The aim of this study was to develop an index assessing the immunomodulatory potential of diet (POLA index) and to test its utility for the prediction of coronavirus disease 2019 (COVID-19) in a group of healthy young people following a traditional or vegetarian diet. Data on body composition, anthropometric measurements, physical activity, dietary intake, and gut microbiota were obtained from 95 adults (mean age, 34.66 ± 5.76 years). There was a strong correlation between the dietary inflammatory index and the POLA index (r = 0.90; p < 0.0001). Based on Cohen's kappa statistic, there was a good agreement in qualitative interpretation between the two indices (kappa = 0.61; p < 0.0001). People on a diet with beneficial immunomodulatory effects had a lower risk of COVID-19 of approximately 80%, as compared with those on a diet with highly unbeneficial immunomodulatory effects. In daily practice, the POLA index might serve as a useful tool for dietitians to identify individuals whose diet is deficient in ingredients for optimal immune system function and change their dietary behavior to ensure optimal immune function that reduces the risk of infection.

Socio-Economic Factors Influencing the Use of Dietary Supplements by Schoolchildren from Malopolska Voivodship (Southern Poland).

The use of regular supplementation may be important in alleviating the potential effects of specific nutrient deficiencies. The aim of this cross-sectional study was to assess the socio-economic and lifestyle factors influencing the administration of dietary supplements to schoolchildren from the Malopolskie voivodship. The study was conducted in March-June 2018 on 332 healthy children and adolescents (187 boys, 145 girls) aged 7-14 from the city and municipality of Niepolomice and the city of Kraków. The mean age of the subjects was 10.35 + 1.64 years. In order to assess their diet, a questionnaire was completed, by the parents or the child, on the frequency of consumption of specific products and foods (Food Frequency Questionnaire, FFQ) with added questions on the supplements provided. In assessing nutritional status, basic anthropometric measurements were taken and the BMI index was analysed. To check which factors influenced the use of supplements among respondents, the odds ratio (OR) was calculated. Approximately one-third of the total number of subjects (33.8%) took dietary supplements, most often supplements containing vitamins D and C, followed by multivitamin supplements and omega-3 fatty acids. The least common supplements contained calcium and iron. Dietary supplement intake was significantly higher among children living in rural areas compared to city areas (39.3% vs. 26.5% of respondents; p = 0.0150), and among boys compared to girls (37.3% vs. 27.8%; p = 0.048). It was observed that children more often received dietary supplements in multigenerational families and in families where at least one parent did not work. This is related to the place of residence of the respondent. Awareness of the need for, and the safe use of, dietary supplements is necessary among parents of children and adolescents.