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Efficacy of dupilumab for the treatment of severe skin disease in cytotoxic T lymphocyte antigen-4 insufficiency: A role of type 2 inflammation?
Arruda, L Karla; Cordeiro, Daniel L; Langer, Sarah S; Koenigham-Santos, Marcel; Calado, Rodrigo T; Dias, Marina M; Anhesini, Leonardo R; Oliveira, João Bosco; Grimbacher, Bodo; Ferriani, Mariana P L.
J Allergy Clin Immunol Glob ; 2(1): 114-117, 2023 Feb.
Article in English | MEDLINE | ID: mdl-37780100

ABSTRACT

We report on the successful treatment of a severe, recalcitrant dermatitis caused by CTLA-4 insufficiency with dupilumab, raising the possibility of a role of type 2 immunity in clinical conditions associated with CTLA-4 insufficiency.

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