ABSTRACT
Vesicles and bullae developed in six patients with psoriasis while they were undergoing therapy for their psoriasis. Skin biopsy specimens were taken from their lesions and studied for regular histopathologic findings and direct immunofluorescence. These studies confirmed that they had coexistent psoriasis and bullous pemphigoid. A review of the therapy that the patients were given incriminates anthralin, crude coal tar, ultraviolet light, and salicylic acid in the possible cause of the development of their bullous pemphigoid lesions.
Subject(s)
Psoriasis/complications , Skin Diseases, Vesiculobullous/complications , Aged , Anthralin/adverse effects , Dermatologic Agents/adverse effects , Female , Humans , Male , Middle Aged , Psoriasis/pathology , Skin Diseases, Vesiculobullous/etiology , Skin Diseases, Vesiculobullous/pathology , Ultraviolet Rays/adverse effectsABSTRACT
Twenty-six tattoos were treated by salabrasion. The salt was left on the abraded surface from zero to 24 hours. The percentage of residual pigment varied from 50%, when the salt was removed immediately after salabrasion, to 5%, when the salt was left in place for over 12 hours. When the salt was left on for variable periods, some degree of scarring and hypopigmentation occurred in 79% and in 59% of the tattoos, respectively. When the salt was removed immediately after salabrasion, 29% of the tattoos showed scarring and 29% showed hypopigmentation. Our results show that the best method is to remove the salt immediately after salabrasion, but that this form of therapy should only be done on those lesions where the eventual cosmetic result is not important.
