[The experience of application of sociological techniques to the patients of oncologic dispensary].

The issues accumulated in national out-patient care of oncologic patients demand a permanent assessment of the organization and effectiveness of this sector of medical care. The opinions of patients of Moscow oncologic dispensary No2 were analyzed to evaluate the actual condition of oncologic care. The questionnaire was developed to organize a survey of 535 oncological patients.

[Comparison of the efficacy of imidazole-carboxamide and of a combination of nitrosomethylurea, vincristine and dactinomycin in disseminated melanoma]. / Sravnenie éffiktivnosti imidazol-karboksamida i kombinatsii nitrozometilmocheviny, vinkristina, daktinomitsina pri disseminirovannoi melanome.

A randomized cooperative study comparing 2 regimens of chemotherapy (DTIC--150mg/m2 iv days 1, 2, 3, 4, 5 and a combination of vincristine--1.4 mg/m2 iv days 1, 8, 15, nitrosomethylurea--200 mg/m2 iv days 3, 5, 10, 12 and dactinomycin--0.3 mg/m2 iv days 1, 3, 5, 8, 10, 12) was carried out in 114 patients with disseminated skin melanoma. A combined chemotherapy course given to 58 patients was followed by complete response (CR) in 8 cases (13.7%) and partial response by over 50% (PR)--in 6 cases (10.4%). In 56 patients treated with DTIC, CR was registered in 4 patients (7.1%) and PR in 9 (16%). Patients resistant to one regimen did not respond to the other.