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2.
No To Hattatsu ; 32(1): 44-8, 2000 Jan.
Article in Japanese | MEDLINE | ID: mdl-10655751

ABSTRACT

We studied the P300 of two epileptic cases with almost continuous diffuse spike-wave discharges on sleep EEG: one with epilepsy with continuous spike-waves during slow wave sleep, and another with atypical benign partial epilepsy. These cases showed a marked prolongation of P300 latencies during nonconvulsive status epilepticus with continuous spike-waves during slow wave sleep. As they improved clinically and electroencephalographically, the latencies became normal. These findings indicate that P300 is a useful method to elucidate the pathophysiology of nonconvulsive status epilepticus with continuous spike-waves during slow wave sleep.


Subject(s)
Electroencephalography , Epilepsy/physiopathology , Event-Related Potentials, P300 , Sleep/physiology , Anticonvulsants/therapeutic use , Child , Epilepsy/drug therapy , Female , Humans , Male , Reaction Time
3.
No To Hattatsu ; 32(1): 56-61, 2000 Jan.
Article in Japanese | MEDLINE | ID: mdl-10655753

ABSTRACT

We report a 13-year-old boy having epilepsy with agammaglobulinemia. He developed without neurological deficits until the age of 4 years, when he had convulsive generalized status epilepticus. He suffered from recurrent infections, and the diagnosis of agammaglobulinemia was made at 5 years. At 8 years, he had complex partial seizures following an aura of epigastric discomfort. EEG recording showed right anteriotemporal spikes. He was diagnosed as having epilepsy and treated by antiepileptic drugs without success. At 10 years, intravenous immunoglobulin therapy was begun to treat recurrent infections. This therapy not only prevented infections, but also resulted in marked improvement of his epilepsy, both clinically and electroencephalographically.


Subject(s)
Agammaglobulinemia/complications , Epilepsy, Temporal Lobe/therapy , Immunoglobulins, Intravenous/administration & dosage , Agammaglobulinemia/genetics , Agammaglobulinemia/therapy , Child , Electroencephalography , Genetic Linkage , Humans , Infections/etiology , Infections/therapy , Male , Recurrence , Treatment Outcome , X Chromosome
6.
Folia Psychiatr Neurol Jpn ; 37(3): 239-44, 1983.
Article in English | MEDLINE | ID: mdl-6676130

ABSTRACT

To investigate the significance of EEG findings relating to the appearance of psychic symptoms in epileptic children, a clinicoelectroencephalographic study was undertaken on 15 cases with psychotic episodes. 1) Psychotic episodes with hallucination and/or illusion were observed, though rarely, in childhood epilepsy. These seemed liable to occur in temporal lobe epilepsy. 2) Three of four patients in the hallucination and illusion group showed frequent epileptic discharges. However, no distinct relation existed between seizure discharges and psychotic episodes. 3) Eight of 11 patients in the dysphoria and excitement group were secondary generalized epilepsy. 4) In the dysphoria and excitement group, psychotic episodes occurred either as a result of the increase in epileptic discharges or conversely as a result of the suppression of epileptic discharges. The former was more frequent. Epileptic discharges tended to be suppressed in the Lennox syndrome and allied conditions relating to psychotic episodes. 5) A forced normalization-like phenomenon mostly resulted from the marked suppression of diffuse slow spike-waves. However, a complete suppression of epileptic discharges was not always noted.


Subject(s)
Electroencephalography , Epilepsy/complications , Psychotic Disorders/complications , Adolescent , Child , Child Behavior Disorders/complications , Epilepsy/diagnosis , Female , Hallucinations/complications , Humans , Illusions/complications , Male
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