ABSTRACT
BACKGROUND: The aim of this study was to investigate the knowledge, attitudes, and practices of the Greek general population toward coronavirus disease 2019 (COVID-19) during the lockdown period in April 2020, to examine factors associated with misperceptions and to determine behavioral patterns that may require interventions. METHODS: A cross-sectional study of the general Greek population (N = 1858) was conducted. A geographically stratified cluster sampling was implemented. A questionnaire was composed consisting of 35 questions. Data collection took place from 15 April to 2 May 2020. A random-digit dialing survey was conducted by 29 interviewers. RESULTS: The majority of respondents (62.7%) answered ≥12/17 questions correctly. Participants aged 18-44 years, male gender, specific occupations (freelancer, unemployed, housewife, retiree) and those who sought information about COVID-19 from less than two sources received lower aggregated scores on knowledge questions. Regarding attitudes toward future vaccination, 18.9% declared that were against it, while 81.1% that they may consider or will be vaccinated. About 40% were not using a face mask and only 42% washed their hands appropriately. CONCLUSION: Adjusting information campaigns targeting especially people below 45 years of age can help to sensitize them and realise their role to control the spread. Further targeted surveys are needed to adjust/design prevention campaigns.
Subject(s)
COVID-19/prevention & control , Communicable Disease Control/statistics & numerical data , Health Knowledge, Attitudes, Practice , Adolescent , Adult , Cross-Sectional Studies , Female , Greece , Humans , Male , Pandemics , Surveys and Questionnaires , Young AdultABSTRACT
Acinic cell carcinoma (ACC) is a low-grade malignant salivary neoplasm. The parotid gland is the predominant site of origin. ACC has a tendency to recur and metastasize, rarely enough to soft tissue as well as other sites. Medical records of a 56-year-old male with a known history of acinic cell carcinoma of the left parotid gland were reviewed. This report aims to highlight the need for early clinical suspicion of the metastatic tendency of parotid gland ACC in patients' soft tissues, and the vigorous oncologic approach to any suspected metastatic deposits, as this is the standard of practice and only treatment.
ABSTRACT
Thrombophilia due to activated protein C resistance (Leiden mutation) is the most common inherited thrombophilic disorder with 5% incidence in whites. Renal transplant of these patients entails a risk of vascular thrombosis soon after the transplant; and acute rejection episodes and graft loss within the first year. We present a case of a successful living-related renal transplant in man with a recent history of repeat episodes of vascular access thrombosis attributed to inherited thrombophilia (heterozygosity for factor V mutation Q506 and homozygosity for mutation T677 for methylene-tetrahydrofolate reductase). Transplant recipient was administered anticoagulation therapy with low molecular weight heparin pre- and postoperatively. No thrombotic or hemorrhagic events occurred posttransplant. A high suspicion of thrombophilic disorders in patients with end-stage renal disease with vascular access thrombotic events should be screened further to prevent failure of a subsequent renal transplant. Inherited thrombophilic disorders may not exclude living-related kidney transplant provided that anticoagulation therapy is admin-istered perioperatively.
Subject(s)
Activated Protein C Resistance/genetics , Blood Coagulation/genetics , Factor V/genetics , Kidney Failure, Chronic/surgery , Kidney Transplantation/methods , Living Donors , Siblings , Activated Protein C Resistance/blood , Activated Protein C Resistance/diagnosis , Activated Protein C Resistance/drug therapy , Aged , Allografts , Anticoagulants/therapeutic use , Blood Coagulation/drug effects , Female , Genetic Predisposition to Disease , Heterozygote , Homozygote , Humans , Kidney Failure, Chronic/diagnosis , Male , Methylenetetrahydrofolate Reductase (NADPH2)/genetics , Middle Aged , Phenotype , Point Mutation , Treatment OutcomeABSTRACT
Cystinuria is an inherited disorder of the dibasic amino acid transport system in the proximal tubule and the small intestine. Two responsible genes have been identified, the SLC3A1 on chromosome 2 and the SLC7A9 on chromosome 19. The inability of renal tubules to reabsorb cystine and the relative insolubility of cystine at physiological urine pH lead to stone formation. Cornerstone of the treatment remains stone prevention with hyperhydration, urinary alkalization, and pharmacologic therapy. Repeated stone formation necessitates urologic interventions, which mainly include minimally invasive procedures. The appropriate management of cystinuria is often challenging and requires close follow-up of the patient.
Subject(s)
Cystinuria/diagnosis , Cystinuria/therapy , Amino Acid Transport Systems, Basic/genetics , Amino Acid Transport Systems, Neutral/genetics , Cystinuria/epidemiology , Cystinuria/genetics , Diet , Genes, Recessive , Humans , Hydrogen-Ion Concentration , Lithotripsy , Nephrostomy, Percutaneous , Quality of Life , Ureteroscopy , Urine/chemistryABSTRACT
We present a case of a thrombus formation within the left ventricle of a patient with a normal heart, who had previously been receiving high doses of erythropoietin for an inappropriately prolonged period.
